We evaluated the ability of human maternal and cord serum antibodies to protect mice challenged with live Escherichia coli serotype O6:K2ac (E. coli O6). Mice received paired maternal or cord serum pools before a challenge with E. coli O6 to evaluate the mortality rate. All the pools were able to protect the animals challenged with bacteria except the test group from paired maternal and cord se...

background: the infection in the neonatal period is a significant cause of mortality in the preterm neonates. the transfer of the immunoglobulin from mother to fetus occurs mainly after 32 to 34 weeks of gestation. therefore, preterm neonates are relatively immune compromised. the aim of the study was to evaluate the impact of intravenous immunoglobulin on mortality rates reduction in preterm n...

Amyloidosis is a protein conformational disease caused by the deposition of extracellular insoluble fibrils which derived from misfolded precursor proteins. The kidney organ most commonly involved in amyloidosis, common types renal amyloidosis include immunoglobulin light chain (AL), amyloid A (AA) and leukocyte chemotactic factor 2 (ALECT2). Previous studies revealed that deposits are often ac...

background: diagnosis of food allergy is difficult in children. food allergies are diagnosed using several methods that include medical histories, clinical examinations, skin prick and serum-specific immunoglobulin e (ige) tests, radio-allergosorbent test (rast), food challenge, and supervised elimination diets. in this study we evaluated allergies to cow's milk, egg, peanut, and fish in c...

BACKGROUND In recent years, increased serum immunoglobulin E (IgE) concentration in patients with cardiovascular diseases has been generating more and more interest. It is as yet unknown, however, if the increased IgE level is a marker of future coronary incidents and whether it may be regarded as an ischemic heart disease risk factor, or if it is indicative of the participation of antibodies i...

Asthma is an inflammatory airway disorder, traditionally subdivided into extrinsic, immunoglobulin E (IgE)-mediated, and intrinsic asthma of unknown aetiology. IgE synthesis requires contact between T- and B-cells and a signal provided by interleukin (IL)-4, which can be modulated by IL-6. The objective of this study was to evaluate the effects of IL-4 and IL-6 on total IgE synthesis by periphe...

INTRODUCTION Idiopathic sclerosing orbital inflammation is a rare and ill-defined heterogeneous entity, and a distinct subset of orbital inflammation. Recently, attention has been focused on immunoglobulin G4-related disease complicated with fibrotic changes in some other organs with high serum immunoglobulin G4 levels. This report presents a case of suspected idiopathic sclerosing orbital infl...