BACKGROUND Increasing evidence suggests that high selenium levels are associated with diabetes and other cardiometabolic risk factors. OBJECTIVES We evaluated the association of serum selenium concentrations with fasting plasma glucose, glycosylated hemoglobin levels, and diabetes in the most recently available representative sample of the U.S. population. METHODS We used a cross-sectional ...

background: allergic diseases have increased during the past decade worldwide. th2 type lymphocyte response is known to play an important role in the process of allergic inflammation. il-4, a mediator of type ii cytokine response increases ige synthesis and interferon gamma, a cytokine of type i response interferes with il-4 and inhibits ige production. selenium is an essential component of glu...

BACKGROUND Epidemiologic and animal studies suggest that selenium may reduce risk of colorectal cancer. However, the epidemiologic data is mainly from relatively small investigations, limiting their interpretation. Although substantial evidence suggests that smoking is a strong effect modifier for other antioxidative nutrients, little is known about smoking-selenium interactions in colorectal t...

Selenium is an essential trace element that has been implicated in cancer risk; however, study results have been inconsistent with regard to colon cancer. Our objectives were to 1) investigate the association between selenium and colon cancer, 2) evaluate possible effect measure modifiers, and 3) evaluate potential biases associated with the use of postdiagnostic serum selenium measures. The No...

A community-based, cross-sectional survey was conducted in the South Island of New Zealand to assess the dietary and biochemical selenium status of children (n = 136) and their mothers (n = 302), and to assess factors influencing selenium status. Serum and plasma samples from children and their mothers were analyzed for selenium using graphite furnace atomic absorption spectrometry. Dietary sel...

PURPOSE Febrile seizures (FS) are seizures that occur between the age of 6 and 60 months, but its pathophysiology still is not fully understood. There is limited information about the correlation between levels of selenium and leptin with FS. This study aimed to determine the relationship between serum levels of selenium and leptin in children with FS. METHODS This case-control study was cond...

Effects of sodium selenite (SS) in offspring of broiler breeders has been reported, but the comparison between SS and different level of methionine on offspring has received limited, so this study was conducted to investigate sodium selenite and methionine effects on concentration of selenium in egg and serum of Iranian native broiler breeders. An experiment was conducted in 3 × 3 factorial exp...

Various epidemiological and clinical researches have been carried out in order to find out the relationship between selenium deficiency and other diseases, mainly cardiovascular diseases and certain types of cancer. In this study, we have aimed at determining serum selenium levels of the patients with acute myocardial infarction (A. M.I.), coronary artery disease (C.A.D), and the healthy contro...

The association between serum selenium concentration and risk of cancer was studied in a nested case control study. Case control pairs came from a population of 9364 people examined in 1979. During the six year follow up, 60 men and women aged between 20-54 at the time of blood sampling, who had been free of malignant disease, developed cancer. The mean serum selenium concentration of 1.56 mumo...

A deficiency of dietary selenium leads to immotile, deformed sperm and infertility in rats, whereas supplementation of the diet with selenium compounds has been associated with both beneficial and deleterious effects on sperm function, depending on the chemical form of selenium. We conducted a randomized, controlled, and blinded intervention study on the effects of selenium in food on semen qua...