PURPOSE To test the hypothesis that rod-mediated visual thresholds at 10 degrees eccentricity are elevated in children with histories of mild retinopathy of prematurity (ROP). METHODS Dark-adapted thresholds for detection of 50 msec, 2 degrees diameter spots at a 10 degrees eccentric site, and at a peripheral reference site, 30 degrees eccentric, were measured in 20 children with a history of...

A study of 866 vaginal swabs from non-pregnant women showed that 167 (19.3%) contained Group B beta-haemolytic streptococci, with a predominance of Types 3 (31.4%) and Ib (25.2%). The incidence of severe neonatal infections due to Group B streptococci during a 3 1/2 year period at The Prince of Wales Hospital was examined, and a study was made of the distribution of serotypes and associated cli...

In this article, the growing problem of retinopathy of prematurity (ROP) worldwide, treatments for severe ROP including standard-of-care laser treatment, and the need for new treatments are discussed. Also discussed are the reasons to consider inhibiting the vascular endothelial growth factor (VEGF) signaling pathway in severe ROP and the concerns about broad VEGF inhibition. Finally, the poten...

Abstract: Preeclampsia contributes significantly to maternal & perinatal morbidity and mortality. Objective: To study maternal & fetal outcome in preeclampsia. Method: Case records of 168 women with preeclampsia, out of which 58 had severe preeclampsia were analysed. This retrospective observational study was conducted at B.J. government medical college, Pune, during period of 1st March 2...

Gestational pemphigoid is a rare pruritic bullous pregnancy associated dermatosis caused by autoantibodies against placental and dermal collagen XVII. Clinically, it is characterized by severe pruritus and blisters on abdominal skin and extremities. Immunofluorescence analysis of perilesional skin is used in the diagnostics and maternal serum BP180-levels reflect the disease activity. Topical s...

Introduction: The prevalence of retinopathy of prematurity is expected to increase along with the developing of premature infants’ care and better prognosis of these infants. The aim of this study was to evaluate the prevalence of retinopathy of prematurity in preterm infants. Methods: According to this cross-sectional study, one same ophthalmologist examined the eyes of all the babies at 4 we...

PURPOSE Retinopathy of prematurity (ROP) is a leading cause of visual loss in the pediatric population. Mutations in the Norrie disease gene (NDP) are associated with heritable retinal vascular disorders, and have been found in a small subset of patients with severe retinopathy of prematurity. Varying rates of progression to threshold disease in different races may have a genetic basis, as rece...

Objective To explore the etiology, incidence and methods to prevent and treat severe retinopathy of prematurity (ROP), which is rapidly becoming a threat to the vision of babies in areas of the world where increasing numbers of premature babies are surviving. Data sources The data used in this review were mainly from Medline and PubMed published in English. The search term was “retinopathy of p...