BACKGROUND Excessive bleeding may complicate congenital cardiac defects. To explain the pathogenesis of this abnormality, we evaluated selected parameters of primary hemostasis in patients with aortic valve stenosis before and after corrective surgery. METHODS AND RESULTS We examined shear-induced platelet aggregation with the filter aggregometer test and von Willebrand factor (vWF) structure...

A layer-wise third order shear and normal deformable plate/shell theory (TSNDT) incorporating all geometric nonlinearities is used to study finite transient deformations of a curved laminated beam composed of a St. Venant–Kirchhoff material. In the TSNDT all displacement components of a point are expressed as 3rd order polynomials in the thickness coordinate in each layer while maintaining the ...

For a plate subject to stress boundary condition, the deformation determined by the Reissner–Mindlin plate bending model could be bending dominated, transverse shear dominated, or neither (intermediate), depending on the load. We show that the Reissner–Mindlin model has a wider range of applicability than the Kirchhoff–Love model, but it does not always converge to the elasticity theory. In the...

Particles transported in fluid flows, such as cells, polymers, or nanorods, are rarely spherical. In this study, we numerically and theoretically investigate the dispersion of an initially localized patch passive elongated Brownian particles constrained to one degree rotational freedom a two-dimensional Poiseuille flow, demonstrating that exhibit enhanced longitudinal dispersion. shear rods tra...

Linear stability analysis of the capillary instability of a viscoelastic liquid thread was carried out by Funada and Joseph (2003), who assumed irrotational flow but retained the effect of viscoelasticity (viscoelastic potential flow, VPF). They compared their results with the unapproximated normal mode solution of the linearized fully viscoelastic flow (FVF). The comparison showed that the gro...

There has been conflicting data in the literature regarding the use of wide navigator echo (NE) acceptance windows in combination with adaptive motion correction for magnetic resonance coronary angiography (MRCA). This in part may be due to the use of a fixed correction factor when applying the adaptive motion-correction algorithm, which may potentially result in miscorrection of the imaging sl...

Abstract We report on laboratory experiments investigating the dynamics of a free fluid surface in cylindrical tank with rotating bottom plate. The shear instability system creates polygonal structures, which propagate around domain, along fixed vertical sidewalls. analyze wavelengths and drift rates these patterns, are known from previous literature to be created by complex interplay between c...

Background: Estimating dosimetric parameters for small fields under non-reference conditions leads to significant errors if done based on conventional protocols used for large fields in reference conditions. Hence, further correction factors have been introduced to take into account the influence of spectral quality changes when various detectors are used in non-reference conditions at differen...

Mammary tumors and malignant breast cancer cell lines over-express the coagulation factor, tissue factor (TF). High expression of TF is associated with a poor prognosis in breast cancer. Tissue factor pathway inhibitor (TFPI), the endogenous inhibitor of TF, is constitutively expressed on the endothelium. We hypothesized that TF-expressing tumor cells can bind to immobilized recombinant TFPI, l...

Monolayers of human umbilical vein endothelial cells were activated with 50 U/mL interleukin-1alpha (IL-1alpha) for 3 hours and simultaneously conditioned with shear stresses of 0, 0.68, or 13.2 dyne/cm(2) in a parallel-plate flow chamber. In the presence of an inflow buffer containing 100 nmol/L factor X and 10 nmol/L factor VII, production of factor Xa, a measure of functional tissue factor (...