The passive K influx in low K(LK) red blood cells of sheep saturates with increasing external K concentration, indicating that this mode of transport is mediated by membrane-associated sites. The passive K influx, iMLK, is inhibited by external Na. Isoimmune anti-L serum, known to stimulate active K transport in LK sheep red cells, inhibits iMLK about twofold. iMLK is affected by changes in int...

IN establishing the diagnosis of tuberculosis, the demonstration of the infecting agent by microscopical and modern culture techniques is the method of choice. Many attempts have also been made to establish a diagnosis by such serological means as precipitation or the fixation of complement, but all these methods have proved unsatisfactory, and none are in common use. In 1948, Middlebrook and D...

After massive hemorrhage, adult sheep with genotypically low potassium (LK) red cells temporarily produce high potassium (HK) cells with ouabain-sensitive K+ pump fluxes equivalent to mature HK red cells. In light of recent reports of different red cell volume populations accompanying the HK-LK transition also occurring in newborn LK sheep and the unresolved controversy over the effect of anti-...

Tyler1 showed that photo-oxidation could cause antisera to become nonprecipitating and nonagglutinating without destroying the ability of the antibodies to combine with the specific antigen. This was shown by the fact that treated antiserum could inhibit specifically agglutination or precipitation by corresponding untreated serum. On the basis of the mutual multivalence theory of Marrack,2 Heid...

OBJECTIVE This study was designed to characterize the DNA polymorphisms of the melanocortin-1 receptor (MC1R) gene in indigenous Saudi Arabian sheep breeds exhibiting different color coats, along with individuals of the Sawaknee breed, an exotic sheep imported from Sudan. METHODS The complete coding region of MC1R gene including parts of 3' and 5' untranslated regions was amplified and sequen...

Cyclophosphamide significantly diminished the canine humoral antibody response to sheep red blood cells and tended to prevent arterial lesions in renal homografts. However, cyclophosphamide failed to prolong renal homograft survival when administered to dogs as the sole immunosuppressive agent, and it did not add to the effectiveness of azathioprine when given as a supplement to the azathioprin...

Lipide extracts of the red cells of several animal species have been analyzed chromatographically. Genetically determined differences in phospholipide composition were found. Lecithin is absent from the cells of ox, sheep, and goat. Cells containing lecithin are susceptible to the direct hemolysin of cobra venom while cells not containing lecithin are resistant. The facts indicate that the dire...

An outbreak of leptospirosis in sheep is recorded as the first epidemic of ovine leptospirosis in Egypt. The sick animals showed typical symptoms such as fever, jaundice, red urine and abortion, with a fatal course. Acute and convalescent sera were tested for demonstration of seroconversion using the microscopic agglutination testto confirm infection. Long-acting tetracycline was successfully u...

In response to repeated injections of sheep red blood cells, C57BL/10J mice produce predominantly 19S antibody in increasingly higher amounts, while A/J mice initially produce 19S antibody and then switch to produce increasing 7S antibody titers. In an F(1) generation all mice responded like the C57BL/10J mice. Backcross data implied genetic control involving at least three loci.

Case Description- A five-year-old Iranian cross-breed ewe with a dark red and soft mass on gingiva of mandibular region was presented to the Islamic Azad University of Tabriz Veterinary Medical Teaching Hospital. Macroscopically, a dark red, pedunculated, round-shaped and soft mass less than 1.5 centimeter on gingival compartment of right midlateral edge was observed. Temperature, heart rat...