نتایج جستجو برای: shigella flexneri

تعداد نتایج: 6203  

Journal: :PLoS Pathogens 2008
Atsuko Fukazawa Carmen Alonso Kiyotaka Kurachi Sonal Gupta Cammie F. Lesser Beth Ann McCormick Hans-Christian Reinecker

Shigella flexneri has evolved the ability to modify host cell function with intracellular active effectors to overcome the intestinal barrier. The detection of these microbial effectors and the initiation of innate immune responses are critical for rapid mucosal defense activation. The guanine nucleotide exchange factor H1 (GEF-H1) mediates RhoA activation required for cell invasion by the ente...

Journal: :Journal of clinical microbiology 1992
D Islam A A Lindberg

A combination of immunomagnetic separation (IMS) and a polymerase chain reaction (PCR) procedure was used for direct isolation and identification of Shigella dysenteriae type 1 and Shigella flexneri from feces. Immunomagnetic particles were coated with monoclonal antibody MASFB, which is specific for a common epitope of the O polysaccharides of S. dysenteriae type 1 and S. flexneri. Bacteria bo...

Background: Shigella spp. are gram negative bacteria, which are of global public health importance. The growing of multidrug-resistant Shigella isolates are a major problemaround the world. Methods: Overall, 50 isolates of Shigella spp. from children diarrheic stools w...

Journal: :PLoS Medicine 2006
Lorenz von Seidlein Deok Ryun Kim Mohammad Ali Hyejon Lee XuanYi Wang Vu Dinh Thiem Do Gia Canh Wanpen Chaicumpa Magdarina D Agtini Anowar Hossain Zulfiqar A Bhutta Carl Mason Ornthipa Sethabutr Kaisar Talukder G. B Nair Jacqueline L Deen Karen Kotloff John Clemens

BACKGROUND The burden of shigellosis is greatest in resource-poor countries. Although this diarrheal disease has been thought to cause considerable morbidity and mortality in excess of 1,000,000 deaths globally per year, little recent data are available to guide intervention strategies in Asia. We conducted a prospective, population-based study in six Asian countries to gain a better understand...

2018
Heleen Joséphine Schuster Michelle Gompelman Wim Ang Albertus Jozef Kooter

A 45-year-old man was presented at the emergency department with altered neurological status and a 1-day history of diarrhoea and fever. The patient's sexual history revealed multiple male partners. As bacterial meningitis or viral encephalitis was suspected, treatment was started accordingly. Cerebrospinal fluid investigations only showed a slight increase of leucocytes, and microbiological st...

Journal: :Infection and immunity 2016
Natasha Weatherspoon-Griffin Helen J Wing

The SlyA transcriptional regulator has important roles in the virulence and pathogenesis of several members of the Enterobacteriaceae family, including Salmonella enterica serovar Typhimurium and Escherichia coli. Despite the identification of the slyA gene in Shigella flexneri nearly 2 decades ago, as well as the significant conservation of SlyA among enteric bacteria, the role of SlyA in Shig...

2013
Qiangzheng Sun Ruiting Lan Jianping Wang Shengli Xia Yiting Wang Yan Wang Dong Jin Bo Yu Yuriy A. Knirel Jianguo Xu

Shigella flexneri is the major cause of bacterial shigellosis in developing countries. S. flexneri is divided into at least 19 serotypes, the majority of which are modifications of the same basic O-antigen by glucosylation and/or O-acetylation of its sugar residues by phage encoded serotype-converting genes. Recently, a plasmid encoded phosphoethanolamine (PEtN) modification of the O-antigen ha...

2017
Leili Shokoohizadeh Gholam Abbas Kaydani Alireza Ekrami

Aim In This study focused on the detection of dominant clones and genetic relationship of Shigella spp. isolated from children with diarrhea in the main pediatric hospital in Ahvaz by multi-locus sequence typing (MLST) technique. Background Shigellosis is considered as one of the problematic bacterial infections for public health in the world. Khuzestan province in the Southwestern part of Ir...

Journal: :Antimicrobial agents and chemotherapy 1986
J M Martínez-Salazar G Alvarez M C Gómez-Eichelmann

The frequencies of tetracycline resistance determinants of the classes A, B, C, and D were determined in 53 non-lactose-fermenting clinical isolates. The most frequent class of determinant in Salmonella typhimurium and Shigella flexneri strains was class B; however, the predominant determinant in Shigella sonnei strains was class C.

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید