نتایج جستجو برای: shortening mechanism
تعداد نتایج: 582646 فیلتر نتایج به سال:
In one patient reprodncibk episodes of sMal tachyear(200 msec, control; 70 msec, atropine) and sustained dia conld be elicited via programmed atrial premature atrial tachycardia no longer could be elicited. These dcpoluizations. Evllodion of the elechpphysiologic studies mpport the concept that h a t t i a l reciprocation shldks suggested that the most tikely mechanism was can be a mechanism re...
Whether contractility of bronchial smooth muscle cells (BSMC) from asthmatic subjects is significantly altered has never been validated. We tested the hypothesis that such BSMC show increased contractility. Cells were isolated from endobronchial biopsies. BSMC shortening was measured under an inverted microscope. Statistically significant increases in maximum shortening capacity (Delta L max) a...
There is increasing evidence suggesting that short telomeres and subsequent genomic instability contribute to malignant transformation. Telomere shortening has been described as a mechanism to explain genetic anticipation in dyskeratosis congenita and Li-Fraumeni syndrome. Since genetic anticipation has been observed in familial breast cancer, we aimed to study telomere length in familial breas...
Reproducible left ventricular dimensions were found by M-mode echocardiography in eight healthy men in the semisupine position during two maximal bicycle exercise tests, performed with four hours interval. Left ventricular end-diastolic dimension did not increase during maximal exercise, while fractional shortening increased by a decrease in end-systolic dimension. Twelve men studied by the sam...
BACKGROUND/AIMS Neuronostatin, derived from the somatostatin preprohormone, was recently identified to be produced by several tissues exerting a role in cardiovascular regulation and metabolism. Nonetheless, the precise mechanism behind neuronostatin-elicited myocardial responses remains elusive. METHODS This study was designed to elucidate the impact of neuronostatin on cardiac contractile f...
Telomeres repress the DNA damage response at the natural chromosome ends to prevent cell-cycle arrest and maintain genome stability. Telomeres are elongated by telomerase in a tightly regulated manner to ensure a sufficient number of cell divisions throughout life, yet prevent unlimited cell division and cancer development. Hoyeraal-Hreidarsson syndrome (HHS) is characterized by accelerated tel...
Problem statement: Ad hoc Networks are wireless networks without any fixed infrastructure. The network topology changes frequently and unpredictably due to the random movement of the nodes. The Ad Hoc on Demand Distant Vector Routing (AODV) protocol works in a dynamic fashion, by establishing a route on demand and continues that route until it breaks. Due to the changing network topology of ad ...
The size and the performance of the left ventricle were examined in six conscious dogs early (within 1 week) and late (average 7 weeks) after the production of a large infrarenal arteriovenous fistula. Radiopaque beads were implanted near the endocardium of the left ventricle, and in each study the end-diastolic pressure was adjusted to 22 mm Hg by transfusion or bleeding. The shortening of the...
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