PURPOSE The first double-blind, placebo controlled trial in the United States of the Self-Esteem And Relationship questionnaire revealed that treatment with sildenafil citrate improves erectile function and measures of quality of life in men with erectile dysfunction. We investigated long-term improvement, and correlations between improved erectile function and confidence, self-esteem and sexua...

Sildenafil (Viagra) has been developed as a drug to treat male impotence. It has also been used to reduce symptoms (e.g. improved exercise capacity) in patients with pulmonary arterial hypertension. A case of subarachnoid haemorrhage (SAH) following the illicit use of sildenafil is reported.

OBJECTIVES To determine the minimal time to successful intercourse after taking sildenafil citrate for erectile dysfunction (ED). METHODS Male patients with ED (mean age 60 years; mean ED duration 7.0 years) who were successfully treated with sildenafil (100 mg) for 2 months or longer were randomized to sildenafil (n = 115) or placebo (n = 113) for 4 weeks of double-blind treatment. Using a s...

A facile and sensitive colorimetric detection method for sildenafil citrate (SLDC) has been developed by using polyvinyl alcohol-citrate-stabilized silver nanoparticles (PVA-Cit-AgNPs). The sensitivity selectivity of were investigated in detail. PVA-Cit-AgNPs could be induced to aggregate immediately the presence SLDC, especially after addition 0.1 M HCl solution. SLD detected response AgNPs th...

Volume 33, no. 9 treatment. Raynaud's phenomenon in patients with systemic sclerosis: a potential Thermographic and symptomatic effect of a single dose of sildenafil citrate on Namita Kumar, Bridget Griffiths and John Allen http://www.jrheum.org/content/33/9/1918.citation J Rheumatol 2006;33;1918-1919 http://www.jrheum.org/alerts 1. Sign up for TOCs and other alerts http://jrheum.com/faq 2. I...

After launching of Sildenafil Citrate, the last invention of 20 century, in 1998, oral PDE5 inhibitor has been established as first line treatment of erectile dysfunction (ED) and shift new paradigm of diagnosis and treatment of ED. The big success of sildenafil in pharmaceutical R&D induced the consecutive development S28 Translational Andrology and Urology, Vol 4, Suppl 1 August 2015 © Transl...

OBJECTIVES Hypotestosteronemia has been reported in approximately half of type 2 diabetic men in general. This study aims to assess serum total testosterone levels in type 2 diabetics with erectile dysfunction and to correlate the degree of improvement between sildenafil citrate and testosterone levels. METHODS A cross sectional and prospective comparative interventional study was conducted a...

Aim: To investigate the protective effect of sildenafil citrate, a selective inhibitor of cyclic guanosine monophosphate-specific phosphodiesterase, on gastric mucosal damage induced by cold restraint stress (CRS) in rats. Further, the study was extended to investigate some possible mechanisms underlying this effect. Material and Methods: Forty rats were randomly divided into 4 groups. Normal c...