The effects of Stöber silica nanoparticles on neuronal survival, proliferation, and on the underlying perturbations in calcium homeostasis are investigated on the well-differentiated neuronal cell line GT1-7. The responses to nanoparticles 50 and 200 nm in diameter are compared. The 50-nm silica affects neuronal survival/proliferation in a dose-dependent way, by stimulating apoptotic processes....

Cadmium telluride (CdTe) and iron oxide nanoparticles doped silica nanospheres were prepared by a multistep method. Iron oxide nanoparticles were first coated with silica and then modified with amino group. Thereafter, CdTe nanoparticles were assembled on the particle surfaces by their strong interaction with amino group. Finally, an outer silica shell was deposited. The final products were cha...

The low-efficiency cellular uptake property of current nanoparticles greatly restricts their application in the biomedical field. Herein, we demonstrate that novel virus-like mesoporous silica nanoparticles can easily be synthesized, showing greatly superior cellular uptake property. The unique virus-like mesoporous silica nanoparticles with a spiky tubular rough surface have been successfully ...

In this paper, we for the first time show the ability of the mesophilic fungus Fusarium oxysporum in the bioleaching of waste material such as Fly-ash for the extracellular production of highly crystalline and highly stable, protein capped, fluorescent and water soluble silica nanoparticles at ambient conditions. When the fungus Fusarium oxysporum is exposed to Fly-ash, it is capable of selecti...

The encapsulation of [Eu(dbm)3phen] into functionalized mesoporous silica nanoparticles (MSN) has been carried out to study the effect of chemical environments on the photoluminescence properties of the rare-earth complex. Surface functionalization was achieved by the reaction of the silanol groups on the surface of mesoporous silica with different organosilylating agents such as (3-aminopropyl...

Objective(s): Study and development of antifouling nanosystem for conjugation of drugs were attracting great attention in recent years. The present study aimed to develop novel curcumin-loaded silica nanoparticles containing zwitterionic coating as an antifouling system to provide protein corona free nanoformulations for curcumin. Materials and Methods: Silica nanoparticles were prepared ...

We report a facile strategy to synthesize silica nanoparticles-coated graphene oxide (GO-SiO2) nanohybrids in a water-alcohol mixture at room temperature. AFM observations revealed that silica nanoparticles with ca. 50 nm in size were densely and evenly covered on graphene oxide sheets. Due to the space layer of silica nanoparticles, micro-scale GO-SiO2 hybrid plates could be individually dispe...

This research presents the interaction of the epoxy polymer diglicydil ether of bisphenol-A (DGEBA) with silica (SiO₂) nanoparticles plus zirconia (ZrO₂) nanoparticles obtained via the sol-gel method in the synthesis of an epoxy-silica-zirconia hybrid adhesive cured with polyamide. ZrO₂ nanoparticles were added to the epoxy-silica hybrid adhesive produced in situ to modify the apparent shear st...

In this work, size-controlled multifunctional mesoporous silica nanoparticles having large surface areas, embedded luminescence, high magnetization, and excellent aqueous dispersity have been successfully prepared by using a simple one-pot synthesis. The size and pore ordering of these particles can be easily controlled based on the number density of Fe3O4 nanoparticle nucleation sites introduc...