There are two different techniques that can be applied for fabricating a nerve cuff electrode: 1. traditionally used silicon rubber tubes or spirals and 2. micromechanical methods. Each technique has its own advantages and restrictions. A hybrid cuff combines desired properties of both: high flexibility, high possible numbers of integrated electrodes, high reproducibility and the ability to emb...

Silicones are used in the plastics industry as additives for improving the processing and surface properties of plastics, as well as the rubber phase in a novel family of thermoplastic vulcanizate (TPV) materials. As additives, silicones, and in particular polydimethylsiloxane (PDMS), are used to improve mold filling, surface appearance, mold release, surface lubricity and wear resistance. As t...

The earliest silicone breast implants were smooth-surface, silicone rubber devices filled with either silicone gel or saline. Because of persistent problems with capsular contracture, polyurethane-covered silicone implants were developed as an alternative. Particularly in the short run, these alternatives proved highly successful at reducing the incidence of capsular contracture. By 1990, polyu...

The ability of cells to invade basement membranes is critical to a number of important biological processes, such as cell metastasis, embryo implantation and early development, and inflammation. Several in vitro invasion assays have been developed so that the invasiveness of cells can be measured. These assays are also used to monitor the altered cell response to stimuli or inhibitors, such as ...