N-acetyl-L-cysteine (NAC) and cysteine have been implicated in a number of human neutrophils' functional responses. However, though Ca(2+) signaling is one of the key signalings contributing to the functional responses of human neutrophils, effects of NAC and cysteine on intracellular calcium concentration ([Ca(2+)]i) in human neutrophils have not been investigated yet. Thus, this study was car...

BACKGROUND As an adjunctive treatment of chronic periodontitis, it seems that the application of periocline or the other antimicrobials is effective against periodontopathogens. In this study, nanoliposomes were investigated as carriers of minocycline hydrochloride and the inhibition effects of minocycline hydrochloride nanoliposomes on the proliferation and lipopolysaccharide (LPS)-stimulated ...

Betaine hydrochloride (BHC), as an ionic salt was found to be an efficient and recyclable catalyst for the one-pot synthesis of 4-thiazolidinediones. The methodology of study was achieved by one-pot condensation of aromatic aldehydes, aromatic amine and mercaptoacetic acid in the presence of betaine hydrochloride (BHC) at reflux temperature in ethanol as solvent. The efficiency of Betaine hydro...

A straightforward, sensitive, and quick spectrophotometric approach was created validated for the detection of Ciprofloxacin hydrochloride, Moxifloxacin Roxithromycin hydrochloride in pure form. These techniques were based upon fact that these antibiotics produced dark yellow ion pairs when combined with bromophenol blue. The binary complex universal buffer solution optimum pH values demonstrat...

BACKGROUND The guanidines asymmetric dimethylarginine (ADMA), a marker of endothelial dysfunction, and its counterpart symmetric dimethylarginine (SDMA), considered inert, are accumulated in chronic kidney disease (CKD). The present study evaluates their effect on monocyte function, since previous data demonstrated leukocyte activation by other guanidino compounds. METHODS The effect of ADMA ...

OBJECTIVES AND BACKGROUND The objective of this study was to investigate the image quality-improving and heart rate-lowering effects of landiolol hydrochloride (a short-acting β1-adrenergic receptor blocker) on coronary computed tomography angiography (CCTA). During CCTA, β-adrenergic receptor blockers have been commonly used to lower heart rate and improve image quality. METHODS A total of 2...

DESCRIPTION Aloxi (palonosetron hydrochloride) is an antiemetic and antinauseant agent. It is a selective serotonin subtype 3 (5-HT3) receptor antagonist with a strong binding affinity for this receptor. Chemically, palonosetron hydrochloride is: (3aS)-2-[(S)-1-Azabicyclo [2.2.2]oct-3-yl]-2,3,3a,4,5,6-hexahydro-1oxo-1Hbenz[de]isoquinoline hydrochloride. The empirical formula is C19H24N2O.HCl, w...

Prior studies of the viscosity of the subunit proteoglycan obtained by dissociative extraction of bovine nasal septum cartilage suggested that the proteoglycan subunit molecule behaves as a rigid rod in aqueous solution over the range of 0.5 to 4.0 M guanidine hydrochloride. A more direct view of dimension and shape can be obtained from light-scattering and viscosity of bovine nasal cartilage p...