The precision of the pointer analysis plays an important role in compiler and other software understanding tools. Contextsensitivity is proven to be an effective methods to improve the precision of the final results of pointer analysis. Many context-sensitive pointer analysis methods have been proposed, however, few of them have been incorporated into production compilers. In Open64 compiler, i...

PURPOSE The purpose of this study is to clarify the lobe-specific nodal metastasis and optimal range of mediastinal nodal dissection in lung cancer patients with skip metastasis. MATERIALS AND METHODS A total of 136 patients with pN2/3 disease were treated between 1988 and 2002, and these patients were divided into two groups according to whether skip metastasis was identified or not. We drew...

AIM To determine the frequency of skip lesions in an unselected series of temporal artery biopsies and compare the results with other series. METHODS The study was a retrospective review of 102 consecutive temporal artery biopsies taken in a five year period (1992-1997) in one large hospital. RESULTS 35 cases (34.3%) showed evidence of active cranial vasculitis with pathological evidence of...

The rod of sarcomeric myosins directs thick filament assembly and is characterized by the insertion of four skip residues that introduce discontinuities in the coiled-coil heptad repeats. We report here that the regions surrounding the first three skip residues share high structural similarity despite their low sequence homology. Near each of these skip residues, the coiled-coil transitions to ...

Pointer analysis is essential for optimizing and parallelizing compilers. It examines pointer assignment statements and estimates pointer-induced aliases among pointer variables or possible shapes of dynamic recursive data structures. However, previously proposed techniques are not able to gather useful information or have to give up further optimizations when overall recursive data structures ...

EBNA2 is essential for Epstein-Barr virus (EBV) immortalization of B lymphocytes. EBNA2 functions as a transcriptional activator and targets responsive promoters through interaction with the cellular DNA binding protein CBF1. We have examined the mechanism whereby EBNA2 overcomes CBF1-mediated transcriptional repression. A yeast two-hybrid screen performed using CBF1 as the bait identified a pr...

Transforming growth factor-beta (TGF-β1) is a potent inductor of matrix metalloproteinase-9 (MMP-9) in transformed cells. Recently, Ski-interacting protein (SKIP) has been described as a regulator of TGF-β1 signal transduction, but its role in the induction of cell malignance by TGF-β1 has not been fully elucidated so far. In the present study, we analyzed the role of SKIP on TGF-β1-induced MMP...

Reversible logic is emerging as a promising computing paradigm, having its applications in low-power CMOS, quantum computing, nanotechnology and optical computing. Firstly, we showed a modified design of conventional BCD subtractors and also proposed designs of carry look-ahead and carry skip BCD subtractors. The proposed designs of carry look-ahead and carry skip BCD subtractors are based on t...