OBJECTIVES As most reports on the gamma knife have related only to short or mid-term results, we decided to evaluate the effectiveness and toxicity of radiosurgical treatment for benign skull base meningiomas in 200 patients with a follow up of 5-12 years to define the role of gamma knife radiosurgery (GKRS) for basal meningiomas and to provide further data for comparison with other treatment o...

Cerebellopontine angle (CPA) tumours are the most common neoplasms in the posterior fossa, accounting for 5-10% of intracranial tumours. Most CPA tumours are benign, with most being vestibular schwannomas. Meningiomas arising from the jugular foramen are among the rarest of all with very few being described in the literature. Treatment options vary considerably as experience with these tumours ...

Background: Meningiomas are the most frequent benign intracranial lesions. The literature review reported that 19-63% of patients with meningioma suffer from preoperative seizures, and 35% experience epileptic seizures as initial symptom. present study attempted to establish risk factors for before surgery supratentorial meningiomas. Objective: To compare predictive skull base meningiomas (SBMs...

Abstract BACKGROUND Genomic studies of high-grade/progressive meningiomas have reported a heterogeneous mutation spectrum. Here, we present genomic survey one the largest multi-institutional cohorts to date. METHODS 850 meningiomas, including 441 WHO grade 2 and 176 3 220 progressive 1 were tested as part clinical testing program by hybridization capture 406 cancer-related genes. Information fr...

The goal of preoperative embolization of intracranial meningiomas is to facilitate their surgical removal by reducing tumor vascularity and decreasing blood loss during surgery. This study is based on personal experience with about 100 embolized meningiomas and on the experience of others. Embolization is performed during the same session as diagnostic angiography. The appropriate embolic mater...