In a prospective descriptive laboratory study, 25 Helping Hand(™) (HH) (10 without and 15 with reminder system) and 50 Medication Event Monitoring Systems (MEMS) (25 with 18-month and 25 with 2-year battery life) were manipulated twice daily following a predefined protocol during 3 consecutive weeks. Accuracy was determined using the fixed manipulation scheme as the reference. Perfect functioni...

Although disrupting reconsolidation may be a promising approach to attenuate or erase the expression of fear memory, it is not clear how the neural state following fear reminder contribute to the following fear extinction. To address this question, we used resting-state functional magnetic resonance imaging (rs-fMRI) to measure spontaneous neuronal activity and functional connectivity (RSFC) fo...

BACKGROUND Mast cells are powerful producers of multiple cytokines and chemical mediators playing a pivotal role in the pathogenesis of various cardiovascular diseases. We examined the role of mast cells in murine models of heart failure due to viral myocarditis, using 2 strains of mast cell-deficient mice. METHODS AND RESULTS Two strains of mast cell-deficient mice, WBB6F1-Kit(W)/Kit(W-v) (W...

IN CHICK AUDITORY HAIR CELLS DURING DEVELOPMENT 5 6 7 Abbreviated title: T-type and L-type Ca current in chick hair cells 8 9 10 Snezana Levic and Didier Dulon 11 12 Equipe Neurophysiologie de la Synapse Auditive, Unité Mixte de Recherche, Inserm 13 U587 et Université Bordeaux Segalen, Institut des Neurosciences de Bordeaux, Centre 14 Hospitalier Universitaire Pellegrin, 33076 Bordeaux, France....

To investigate refractive and axial responses to the shift of focal plane resulting from the interchange of two monochromatic lights separately corresponding to the peak wavelengths of the cones absorption spectrum in retina, fifty 2-week-old pigmented guinea pigs were randomly assigned to five groups based on the mode of illumination: short-wavelength light (SL), middle-wavelength light (ML) a...

We show that the Faddeev-Pyatov SL q (N) differential algebra [1] is a subalgebra of the GL q (N) differential algebra constructed by Schupp, Watts and Zumino [2]. In the paper [1], the bicovariant differential algebra on SL q (N) (see below (10), (11)) with generators {T ij , L ij , ˜ Ω ij } i, j = 1,. .. N has been constructed. The elements T ij are generators of the algebra F un(SL q (N)), w...

BACKGROUND Virtual worlds are rapidly becoming part of the educational technology landscape. Second Life (SL) is one of the best known of these environments. Although the potential of SL has been noted for health professions education, a search of the world's literature and of the World Wide Web revealed a limited number of formal applications of SL for this purpose and minimal evaluation of ed...

Left ventricular hypertrophy (LVH), assessed by ECG, is associated with an increased risk for cardiovascular events among hypertensive subjects. We evaluated the risks of LVH in a Japanese general population including normotensive and prehypertensive subjects. We measured ECG and blood pressure in 10 755 subjects at baseline. The Cornell product (CP) and Sokolow-Lyon (SL) voltage were calculate...

ASTI is a guideline-based decision support system for therapeutic prescribing in primary care with two modes of interaction. The "critic mode" operates as a reminder system to detect non guideline-compliant physician drug orders, whereas the "guided mode" operates on demand and provides physician guidance to help her establishing best recommended drug prescriptions for the management of hyperte...