نتایج جستجو برای: slc30a8

تعداد نتایج: 228  

2013
S. Sharifi S. Daghighi M. M. Motazacker B. Badlou B. Sanjabi A. Akbarkhanzadeh A. T. Rowshani S. Laurent M. P. Peppelenbosch F. Rezaee

Adipocytes hypertrophy is the main cause of obesity and its affliction such as type 2 diabetes (T2D). Since superparamagnetic iron oxide nanoparticles (SPIONs) are used for a wide range of biomedical/medical applications, we aimed to study the effect of SPIONs on 22 and 29 risk genes (Based on gene wide association studies) for obesity and T2D in human adipocytes. The mRNA expression of lipid a...

2014
Nisa M. Maruthur Braxton D. Mitchell

Advances in our understanding of the genetics of type 2 diabetes have been astronomical over the past decade with more than 100 single nucleotide polymorphisms (SNPs) associated with modest increases in diabetes risk and differences in related traits such as fasting glucose (1,2). However, these SNPs have contributed more to elucidating biologic pathways than predicting diabetes risk (3). Nonet...

Journal: :Journal of Clinical Research in Pediatric Endocrinology 2018

2015
Liqing Cheng Dongmei Zhang Lina Zhou Jie Zhao Bing Chen

BACKGROUND Accumulating but inconsistent data about the role of rs13266634 variant of SLC30A8 in type 2 diabetes have been reported, partly due to small sample sizes and non-identical ethnicity. MATERIAL AND METHODS We searched PubMed and Cochrane Library to identify eligible studies and extract data of baseline characteristics, genotype count, odds ratio (OR), and 95% confidence interval (CI...

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