We investigated the number of cigarettes smoked daily, years of smoking, cigarette pack-years, levels of daily exposure to cigarette tar (LECT, mg/day) or nicotine (LECN, mg/day) in 53 male Japanese smokers using a questionnaire and measured each participant's baseline leukocyte DNA damage using the alkaline comet assay. The results showed that the baseline value of peripheral leukocyte DNA str...

BACKGROUND Carbon monoxide (CO) is normally present in the human body due to endogenous production of CO. CO can also be inhaled by exposure to external sources such as cigarette smoke, car exhaust, and fire. The purpose of this study was to investigate CO concentrations in blood from 410 blood donors at the blood center in Umeå, Sweden. To further evaluate the effects of cigarette smoking on C...

We carried out a comparative study to assess the demographic and social characteristics of water pipe (WP) smokers, the association with cigarette smoking and chronic respiratory diseases and the dependence profile on 4 groups: exclusive WP smokers, exclusive cigarette smokers, mixed smokers and absolute non-smokers. Cigarette smoking was statistically significantly higher in WP smokers than no...

STUDY OBJECTIVE The aim was to determine if there was a relationship between cigarette tar yield and rates of chronic cough and chronic phlegm. SETTING 22 districts across Scotland were used for the Scottish Heart Health Study (SHHS) which was conducted between 1984 and 1986 and from which the data for this analysis were obtained. SUBJECTS 10,359 men and women aged 40-59 years were studied....

The manner in which a cigarette is smoked varies considerably between individuals and may be an important determinant of the altered bronchial reactivity observed in cigarette smokers. Twenty smokers were examined to determine the relationship between cigarette smoke inhalation patterns and bronchial reactivity. Inhalation patterns were measured non-invasively with a respiratory inductive pleth...

BACKGROUND Tobacco smoke is a toxic gas-phase cocktail consisting of a broad range of organics, and free radical intermediates. The formation of smoke from a burning cigarette depends on a series of mechanisms, including generation of products by pyrolysis and combustion, aerosol formation, and physical mass transfer processes. METHODS The current study simulates the deposition of particulate...

A 1985 survey of a random sample of faculty at the Yale University School of Medicine investigated smoking prevalence and attitudes. The overall prevalence of cigarette smoking was estimated to be 9.8 percent, much lower than the prevalence in the general population. A higher proportion of women than men were current cigarette smokers. With regard to department affiliation, surgeons were most f...

OBJECTIVES To examine the association between overweight, central obesity and cigarette smoking (total amount of cigarettes smoked [TACS] and status). DESIGN Population-based cross-sectional study. SETTING Administrative villages and neighborhoods (n=45) randomly selected from three urban districts and two rural counties in Nanjing City, China. SUBJECTS AND METHODS A representative sample...

STUDY OBJECTIVE The number of cigarettes smoked per day is an imprecise indicator of exposure to cigarette smoke, and biochemical assessment of exposure is not always feasible. The aim of this study was to develop more accurate measures of self reported active exposure to cigarette smoke. DESIGN Mail survey in 386 smokers, retest at one month in 94 participants (24%), analysis of saliva cotin...

OBJECTIVE To assess the risk of lung cancer in smokers of medium tar filter cigarettes compared with smokers of low tar and very low tar filter cigarettes. DESIGN Analysis of the association between the tar rating of the brand of cigarette smoked in 1982 and mortality from lung cancer over the next six years. Multivariate proportional hazards analyses used to assess hazard ratios, with adjust...