OBJECTIVE Continuous glucose monitoring (CGM) is increasingly used to assess glucose control in diabetes. The objective was to examine how analysis of glucose data might improve our understanding of the role temporal glucose variation has on large-for-gestational-age (LGA) infants born to women with diabetes. RESEARCH DESIGN AND METHODS Functional data analysis (FDA) was applied to 1.68 milli...

We present a new analysis of the currently available orbital elements for the known Kuiper belt objects. In the nonresonant, main Kuiper belt, we Ðnd a statistically signiÐcant relationship between an objectÏs absolute magnitude (H) and its inclination (i). Objects with H \ 6.5 (i.e., radii km for a Z170 4% albedo) have higher inclinations than those with H [ 6.5 (radii km). We have shown that ...

This can of course be solved using algebra. The rst treatise on algebra was written by Diophantus of Alexandria in the 3rd century AD. The term derives from the Arabic al-jabr or literally \the reunion of broken parts." As well as its mathematical meaning, the word also means the surgical treatment of fractures. It gained widespread use through the title of a book ilm al-jabr wa'l-mukabala|the ...

BACKGROUND The risk of gestational diabetes mellitus (GDM) increases substantially with increasing maternal body mass index (BMI). The aim of the present study was to evaluate the relative importance of maternal BMI and glucose levels in prediction of large-for-gestational-age (LGA) births. METHOD This observational cohort study was based on women giving birth in southern Sweden during the ye...

BACKGROUND In 2009, the Institute of Medicine published revised gestational weight gain (GWG) guidelines with changes notable for altered body mass index (BMI) categorization as per World Health Organization criteria and a stated range of recommended gain (11-20 pounds) for obese women. The goal of this study was to evaluate associations between maternal BMI-specific GWG adherence in the contex...

BACKGROUND High levels of serum phosphorus, even within the normal range, have been associated with cardiovascular (CV) morbidity. Low-grade albuminuria (LGA) was demonstrated to be related to increased CV events in various study populations. The present study aimed to investigate the association between serum phosphorus levels and LGA in the general population. METHODS We examined the indivi...

Glioblastomas (GBM) are the most prevalent type of malignant primary brain tumor in adults. They may manifest de novo or develop from low-grade astrocytomas (LGA) or anaplastic astrocytomas. They are characterized by an aggressive local growth pattern and a marked degree of invasiveness, resulting in poor prognosis. Tumor progression is facilitated by an increased activity of proteolytic enzyme...

OBJECTIVE Our goal was to investigate which glucose measurement from the 75-g oral glucose tolerance test (OGTT) has more capability of predicting large for-gestational-age (LGA) newborns of mothers with gestational diabetes mellitus (GDM). SUBJECTS AND METHODS The study group consisted of 118 consecutively pregnant women with singleton pregnancy, patients of Outpatients Department of the End...

Alterations in placental transport may contribute to accelerated fetal growth in pregnancies complicated by diabetes. We studied the activity of the syncytiotrophoblast amino acid transporter system A and the transport of the essential amino acids leucine, lysine, and taurine. Syncytiotrophoblast microvillous plasma membranes (MVMs) and basal plasma membranes (BMs) were isolated from placentas ...

OBJECTIVE To evaluate metabolic syndrome and cardiovascular disease risk factors in prepubertal children born large for gestational age (LGA) to nondiabetic, nonobese mothers. RESEARCH DESIGN AND METHODS At 6-7 years of age, the comparison of various factors was made between 31 LGA and 34 appropriate-for-gestational-age (AGA) children: fibrinogen, antithrombin III, protein C and S, fasting in...