Soy foods, rich in plant estrogens, have been embraced by American women seeking relief from menopause without the breast cancer risk associated with synthetic hormones. Because Asian women consume soy-based diets but have a low incidence of breast cancer, it has been suggested that soy prevents cancer, perhaps by reducing estrogen levels. Asian women living in Asia have serum estrogen levels a...

Soy foods, rich in plant estrogens, have been embraced by American women seeking relief from menopause without the breast cancer risk associated with synthetic hormones. Because Asian women consume soy-based diets but have a low incidence of breast cancer, it has been suggested that soy prevents cancer, perhaps by reducing estrogen levels. Asian women living in Asia have serum estrogen levels a...

As a major food ingredient, soybean provides numerous health benefits, for example, individuals who consume soybean-rich diets exhibit lower incidence of high plasma cholesterol, cancer (including bowel and kidney), diabetes mellitus, and obesity (Carroll and Kurowska, 1995; Friedman and Brandon, 2001; Duranti et al., 2004; Ali et al., 2004; Omini and Aluko, 2005; Kim et al., 2006). However, so...

BACKGROUND Infantile food protein-induced enterocolitis syndrome (FPIES) is a severe, cell-mediated gastrointestinal food hypersensitivity typically provoked by cow's milk or soy. Solid foods are rarely considered a cause. OBJECTIVE To describe the clinical characteristics and natural history of FPIES provoked by solid foods. METHODS Patients with FPIES induced by solid foods were identifie...

High-moisture extrusion of soy protein isolate generates a highly palatable meat substitute. No systematic evaluation of the nutritional quality of soy processed in this manner has been performed. This study compared the growth rate of male and female mice fed diets containing soy protein isolate without extrusion or with high-moisture extrusion. Other measures of overall growth and animal heal...

While epidemiologic studies suggest that soy intake early in life may reduce breast cancer risk, there are also concerns that exposure to soy isoflavones during childhood may alter pubertal development and hormonal profiles. Here, we assessed the effect of a high-soy diet on pubertal breast development, sex hormones, and growth in a nonhuman primate model. Pubertal female cynomolgus monkeys wer...

We investigated the estrogenic activity of various environmental pollutants (xenobiotics), in particular the xenoestrogen o,p-DDT, and compared their effects with those of endogenous estrogens, phytoestrogens, and mycoestrogens on estrogen receptor binding capacity, induction of estrogen end products, and activation of cell proliferation in estrogen-sensitive human breast cancer cells in monola...

More than 90% of the surviving cells of Escherichia coli NCSM were injured after freezing in water at -78 C. Injury was determined by the ability of cells to form colonies on Trypticase soy agar with yeast extract but not on violet red-bile agar and deoxycholate-lactose agar. Exposure of the injured cells to Brilliant Green-bile broth and lauryl sulfate broth prevented subsequent colony formati...

BACKGROUND The aim of this paper was to investigate whether a statistical model could be developed to estimate a "threshold" dose for foods eliciting allergic reactions in susceptible patients. The threshold dose is defined to be one that elicits allergic reactions in a given (small) proportion of susceptible patients, using data from published studies. METHODS Based on data available from th...

Many brands of soy-based infant formulas are commercially available in any supermarket. Soy-based infant formulas have been in use for more than 100 years [1] and continue to be very popular as a nutritional supplement for growing infants. Recent findings in soy research even suggest that the phytoestrogens in soy may contribute to a lowered risk of cardiovascular disease, cancer, and a lesseni...