Polymyositis is a nonsuppurating inflammatory disease of the striated muscle characterized clinically by the presence of proximal muscular weakness that is sometimes associated with pain. 1 This disease falls within a broader category known as idiopathic inflammatory myopathy, which includes the forms of myositis that are secondary to connective tissue disease and neoplasms and myositis with in...

The mass was composed of basaloid cell nests, with ill-defined intercellular limits, that showed nuclei with noticeable pleomorphism, atypia, and frequent mitoses (Figure 2). The nests often contained small tubules or ducts that were occasionally delimited only by spindlelike cells, and in others, also showed malpighian differentiation of the tumor cells around these tubules. Immunohistochemist...

In this study, we used proteomics and biological network analysis to evaluate the potential biological processes and components present in the identified proteins of biopsies from cutaneous leishmaniasis (CL) patients infected by Leishmania braziliensis in comparison with normal skin. We identified 59 proteins differently expressed in samples from infected and normal skin. Biological network an...

INTRODUCTION Cutaneous appendageal tumor can differentiate towards or arise from either pilosebaceous apparatus or the eccrine sweat glands. Appendageal tumors are relatively rare, their clinical appearance is non-specific, and the vast majority are not diagnosed until after excision. Eccrine porocarcinoma (EP), also known as malignant eccrine poroma is a rare adnexal tumor arising from the int...

BACKGROUND Optimal management of cutaneous herpes simplex virus (HSV) and varicellazoster virus (VZV) infections requires rapid, accurate distinction between these pathogens. OBJECTIVE In a mixed-case series of suspected cutaneous herpesvirus infections, we compared the diagnostic utility of viral culture and direct immunofluorescence (DIF) using a panel of fluoresceinated monoclonal antibodi...

background: mycobacterium marinum infection has a worldwide distribution and the organism occupies many aquatic environments. infections in human consist of nodular cutaneous lesions that can progress to tenosynovitis, arthritis, and osteomyelitis. case presentation: a 27-year-old man was presented with a history of swelling and exudative erythematous lesions and pustules of the right forearm. ...

background cutaneous leishmaniasis is a health problem in the world. lesions should be treated on cosmetically or functionally important sites, such as the face and hands. cantharidin is a terpenoid compound produced naturally by beetles of meloidae and oedemeridae families. objectives the current study aimed to investigate the effect of cantharidin on cutaneous leishmaniasis (cl) lesions and i...

Sarcoidosis is multi organ disease with cutaneous manifestation in 20%-35% patients. Cutaneous sarcoidosis has variable manifestations that make it difficult to diagnose. So clinical, histopathologic and laboratory evaluation is needed for diagnosis. Most of cutaneous lesions presents as nodul, maculopapule and plaque. Morpheaform lesion is a rare presentation of cutaneous sarcoidosis. This cas...

To the Editor: In Afghanistan, most cutaneous leishmaniasis cases are caused by Leishmania tropica, which is transmitted anthroponotical-ly by the sandfly Phlebotomus sergen-ti (1). Cutaneous leishmaniasis can have devastating effects on local communities because of its clinical symptoms , i.e., large, multiple, or both, disfiguring lesions, that can lead to social ostracism of affected persons...