Gravimetric, titrimetric, polarographic, optical and radiochemical methods have been reported for the determination of iron(II) and (III). Numerous reagents have also been reported for the spectrophotometric determination of Fe(II); for example, thiocyanate, dipyridine, tripyridine and 1,10-phenanthroline. The 1,10phenanthroline family has been extended to the use of dihydroxy, dimethyl, nitro ...

The spectrophotometric methods for the determination of Zolmitriptanin pure and dosage forms have been described in thispaper. The aim of the present work is to develop simple, sensitive and cost-effective spectrophotometric method for the determination of Zolmitriptan in pharmaceutical formulation. The present methods involve the determination of Zolmitriptanin pharmaceutical dosage at the giv...

The reaction between phenothiazine and 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (DDQ) in the presence of p-toluenesulfonic acid in chloroform was investigated by potentiometry, voltammetry and spectrophotometry, and the reaction pathways were proposed. The conditions for the oxidimetric titration of phenothiazines with a standard chloroform solution of DDQ were optimized and the potentiometric...

Pyridine-4-carboxylic acid hydrazide, commercially known as isoniazid (INH), is an antitubercular drug and is now widely used together with rifampicin and streptomycin for the chemotherapy of tuberculosis. Ritodrine hydrochloride (RTH), chemically, 1-(4-hydroxyphenyl)-2-[2-(4-hydroxyphenyl)ethylamino]propanol is a potent tocolytic drug and is a selective β2-adrenoceptor agonist and is used to c...

Spectrophotometric method for the determination of certain proton pump inhibitors belonging to the benzimidazole class of compounds has been developed. The method is based on the reaction of omeprazole, lansoprazole, pantoprazole, rabeprazole and esomeprazole with iron (III) and subsequent reaction with ferricyanide under neutral condition which yields Prussian blue product with maximum absorpt...

Terbinafine Hydrochloride (TH) is a new potent antifungal agent. UV-spectrophotometric method has been developed for the determination of TH in bulk and in tablet dosage form. For the determination of Terbinafine Hydrochloride, solvent system employed was methanol and wavelength of detection was 223 nm. The aim of this study was to develop simple, sensitive, cost effective, accurate, precise, r...

Terbinafine Hydrochloride (TH) is a new potent antifungal agent. Many spectroscopic methods are developed using organic solvents, but inorganic solvents like hydrochloric acid, sodium hydroxide can also be used for the estimation of APIs depending on their solubility. UV-spectrophotometric method has been developed for the determination of TH in bulk and in tablet dosage form. For the determina...

Although there are numerous methods for quantitative determination of antioxidative vitamins: C, E, and A, there are no methods favourable for the broadly understood analytic practice – they have various faults and limitations or require expensive apparatus. Therefore, we have elaborated modifications of valuable spectrophotometric methods for determination each of those vitamins, which origina...

Psychotropic drugs are an important family of compounds from a medical point of view. Their application in therapy requires methods for the determination in pharmaceutical dosage forms and body fluids. Several methods for their analysis have been reported in the literature. Among the methods, spectrophotometric and electrochemical are very useful for the determination of the drugs. Some of the ...

Numerous heterocyclic azo dyes have been reported for the spectrophotometric determination of Cu(II). Here, we report a new heterocyclic azo dye 1-(2'Chloro-4'-sulphophenyl-3-methyl-4-azo-(2"carboxy-5"-sulphonic acid)-5-pyrazolone [CSMACSP] for the spectrophotometric determination of Cu(II). The method is simple, rapid and sensitive. Light green colour 1:1 (M:L) complex formed between Cu(II) an...