Methyl methanesulfonate (MMS), a direct-acting alkylating agent, is a strong brain carcinogen but a poor hepatocarcinogen in rats. To elucidate the mechanism(s) leading to tissue-specific carcinogenesis in response to MMS, we compared the activation of the stress-activated protein kinases (SAPKs), the c-Jun NH2-terminal kinase (JNK) and p38, in the liver and brain of rats after i.p. injection o...

BACKGROUND AND PURPOSE Although studies have evaluated the differential imaging of moyamoya disease and atherosclerosis, none have investigated the added value of vessel wall magnetic resonance imaging (MRI). This study evaluates the added diagnostic value of vessel wall MRI in differentiating moyamoya disease, atherosclerotic-moyamoya syndrome (A-MMS), and vasculitic-MMS (V-MMS) with a multico...

The Manufacturing Messaging Specification (MMS) protocol is widely used in industrial process control applications, but it is poorly documented. In this paper we present an analysis of the MMS protocol in order to improve understanding of MMS in the context of information security. Our findings show that MMS has insufficient security mechanisms, and the meagre security mechanisms that are avail...

OBJECTIVES To identify Medicare use rates of Mohs micrographic surgery (MMS) and surgical excision for the treatment of nonmelanoma skin cancer (NMSC) and to identify patient, lesion, and geographic characteristics associated with treatment type. DESIGN A retrospective analysis of Medicare beneficiaries. SETTING Surveillance, Epidemiology, and End Results database. PATIENTS Patients under...

Methyl methanesulfonate (MMS) is an anti-carcinogenic drug and its toxicity has been reported in various experimental models. The hsp70s are a family of ubiquitously expressed heat shock proteins. In the recent years, hsp70 has been considered to be one of the candidate genes for predicting cytotoxicity against environmental chemicals. Nowadays emphasis is given to the use of alternatives to ma...

Much have been said about metadata which is “data about data” used for classification and retrieval of information. However, metadata is not created by itself. This paper will present the design, interface and implementation of our own metadata tool called Metadata Management System, MMS that was developed to facilitate the creation, maintenance and storage of metadata. This metadata tool suppo...

Ab&m+--The. petrology and geochemistry of twenty-three chondritic dust particles with masses of l47 pg (sizes 100-400 pm) were recovered from blue ice near Cap Prudhomme, Antarctica, and studied by INAA, ASEM, EMPA, and optical microscopy. Sample selection criteria were irregular shape and (for a subsample) black color, with the aim of stud~ng as many unmelted micrometeo~~s (MI&) as possible. O...

MMS induces diverse rII mutations from a wild-type background in bacteriophage T4. About 56% are base pair substitutions, about 30% are frameshift mutations, and the remainder is a miscellaneous set of rapidly reverting or leaky mutants of unknown composition; but deletions were not detected. MMSinduced forward mutation is sharply reduced by the mutations px and y, which also reduce ultraviolet...

due to its complexity and destructive nature, convection has been subject of many studies and researches among weather phenomena throughout the world. scientists have attempted for decades to generate different types of models to provide the possibility of abating or, at least, reducing convective weather phenomena effects on people’s lives. in south or southwest of iran, people are familiar wi...

We compute the strange and the average up/down quark masses in the quenched approximation of lattice QCD, by using the O(a)-improved Wilson action and operators and implementing the non-perturbative renormalization. Our computation is performed at four values of the lattice spacing, from which we could extrapolate to the continuum limit. Our final result for the strange quark mass is mMS s (2 G...