Motivated by a recently developed technique for measuring soft materials properties at the tip of an embedded needle [Zimberlin, et al., Soft Matter, 2007, 3, 763], the mechanics of elasticity- and surface tension-governed void growth within a neo-Hookean material is explored. Previous efforts to describe this technique relied on a hybrid spherical void/spherical cap approximation, thus assumin...

In this article, we advance a hypothesis for the rupture of thin fibrous cap atheroma, namely that minute (10-mum-diameter) cellular-level microcalcifications in the cap, which heretofore have gone undetected because they lie below the visibility of current in vivo imaging techniques, cause local stress concentrations that lead to interfacial debonding. New theoretical solutions are presented f...

For a convex body of given volume in spherical space, the total invariant measure of hitting great subspheres becomes minimal, equivalently the volume of the polar body becomes maximal, if and only if the body is a spherical cap. This result can be considered as a spherical counterpart of two Euclidean inequalities, the Urysohn inequality connecting mean width and volume, and the Blaschke-Santa...

W political leaders in the European Union, Canada, Australia, Japan, and the U.S. Congress move toward cap-and-trade systems as their preferred approach for achieving meaningful reductions in emissions of CO2 and other greenhouse gases, there is a lively debate among economists, many of whom have been critical of the cap-and-trade approach in the climate context and have endorsed carbon taxes i...

Numerical simulations of contaminated spherical drops falling through a stagnant liquid at low Reynolds numbers are carried out using the finite difference method. The numerical results used to describe behavior surfactant concentrations and understand effects on fluid motions in detail. predicted interfacial concentration, ?, is almost zero for angles, ?, below certain value (the stagnant-cap ...

objective(s): adeno-associated virus type 2 (aav2) vectors are widely used for both experimental and clinical gene therapy. a recent research has shown that the performance of these vectors can be greatly improved by substitution of specific surface-exposed tyrosine residues with phenylalanines. in this study, a fast and simple method is presented to generate aav2 vector helper plasmids encodin...

For multicomponent vesicles, the line tension of domain boundaries and the component-dependent elastic properties (e.g., spontaneous curvatures) are the two most important factors that mediate the budding behaviors of these vesicles. This paper especially focuses on their effects on the budding types and the budding number of a two-component vesicle. We found that the budding number is mainly d...