background: tumors of the central nervous system (cns) are a heterogeneous group of neoplasms with different prevalence in different sex and age groups and various parts of cns. objectives: determining the relative frequency of different types of cns tumors in different ages, sex and cns anatomical locations. materials and methods: this retrospective study was performed using pathological repor...

Objective(s): Neurotrophic factors secreting cells (NTS-SCs) may be a superior cell source for cell-based therapy in neurodegenerative diseases. NTS-SCs are able to secrete some neurotrophic Such as nerve growth factor and glia-derived neurotrophic factor. Our primary aim was to assess transplantation of neurotrophic factor secreting cells derived from human adipose-derived stem cells (hADSCs) ...

background: over the years, various types of orthoses have been designed to assist subjects with spinal cord injury (sci) to stand and walk. however, the functional performance of the orthoses has not been adequate, that is, patients experience stability problems, consume excessive energy during ambulation, and generally require assistance in donning and doffing the devices. this research is ai...

background and aim : acute injuries of the spine and spinal cord are causing the greatest amount of disability. they produce high cost outcomes for patients and society psychologically and economically. knowing the epidemiology of these injuries play an important role in planning for prevention and conservative treatment. but now, we have little information about this in our country. the aim of...

BACKGROUND To compare the clinical characteristics, and short-term outcome of spinal cord infarction and cerebral infarction. METHODS Risk factors, concomitant diseases, neurological deficits on admission, and short-term outcome were registered among 28 patients with spinal cord infarction and 1075 patients with cerebral infarction admitted to the Department of Neurology, Haukeland University...

Methylprednisolone is a synthetic glucocorticoid with a potent and long-acting anti-inflammatory, antiallergic and immunosuppressant. Its mechanism of action of methylprednisolone is the result of many cellular changes. Methylprednisolone is used in many diseases, such as rheumatic diseases, autoimmune diseases, allergic, anaphylactic shock, asthma. Methylprednisolone was also used in patients ...

Ischemic tolerance is an endogenous neuroprotective phenomenon induced by sublethal ischemia. Ischemic preconditioning (IPC), the first discovered form of ischemic tolerance, is widely seen in many species and in various organs including the brain and the spinal cord. Ischemic tolerance of the spinal cord is less familiar among neurosurgeons, although it has been reported from the viewpoint of ...

Diffusion-weighted MR imaging may increase the sensitivity and specificity of MR imaging for certain pathologic conditions of the spinal cord but is rarely performed because of several technical issues. We therefore tested a novel phase-navigated spin-echo diffusion-weighted interleaved echo-planar imaging sequence in seven healthy volunteers and six patients with intramedullary lesions. We per...

Neuromyelitis optica (NMO) is an autoimmune disorder of the central nervous system, that predominantly affects the spinal cord and the optic nerve. Its key features include transverse myelitis, commonly associated with extensive inflammation spanning three or more consecutive vertebral segments. Longitudinal extensive spinal cord lesions can also occur in systemic autoimmune diseases, infection...

background & importance: acute autonomic system impairment can be dangerous and life-threatening, and a clinician should be aware of its occurrence possibility. according to the anatomy of this system, spinal cord lesions could disturb its function. there are many reports of autonomic dysreflexia in spinal cord i njuries especially spinal cord trauma. case presentation: a 28 year-old man with a...