Background: Following spinal cord injury, reactive astrocytes upregulate chondroitin sulfate proteoglycans (CSPGs) which act as a barrier to neuronal repair and regeneration. Therefore, enzymatic digestion of CSPGs by chondroitinase ABC (cABC) is a key strategy in the treatment of spinal cord injury. Furthermore, cABC has been shown to attenuate post spinal cord injury inflamma...

Compound action potential (CAP) of spinal cord represents valuable properties of neural fibers including excitability, rate of myelination and membrane integrity. These properties are measured using amplitude, latency and area under curve of CAPs recorded from spinal cord. Here, the isolated spinal cord was set in a double sucrose gap (DSG) chamber and its response to intracellular stimulation ...

The authors describe a case of choriocarcinoma that metastasized to the cerebral cortex, vertebral body, and intramedullary spinal cord. A 21-year-old woman presented with sudden headache, vomiting and a visual field defect. Brain computed tomography and magnetic resonance examinations revealed an intracranial hemorrhage in the left temporo-parietal lobe and two enhancing nodules in the left te...

acute injuries of the spine and spinal cord are among the most causes of severe disability and death after trauma. data about spine fracture with or without cord damage are different. the aim of this study was to determine epidemiology and demographics of spinal injury in main trauma center, guilan, an iranian province. the present study was a descriptive study of all cases of traumatic spine i...

Background: Anatomical and histological studies of the spinal cord have always garnered anatomists’ attention because of their high importance in various fields of veterinary medicine, zoology and behavioral science. OBJECTIVES: This work was conducted to understand the detailed histomorphometric aspects of the spinal cord of Indian gray mongoose (Herpestes edwardsii). METHODS: Six adult Indian...

Abstract INTRODUCTION Central nervous system (CNS) metastasis from nasopharyngeal carcinoma (NPC) is rare and presents with high morbidity mortality. As a entity, few patients CNS NPC have been reported, no studies were available on treatment prognosis. Based our clinical experience, early diagnosis incorporation of clear palliative plan imperative in providing holistic care for locally-invasiv...

Spinal cord injury is a devastating chronic condition resulting in temporary or permanent motor,sensory or autonomic dysfunction of the cord. The manifestation of spinal cord injury based onthe severity and involved areas could be different. Numerous studies have demonstrated thatbradycardia, hypotension, and orthostatic hypotension are present insignificant number ofpat...

brown tumors may occur secondary to hyperparathyroidism in patients with chronic renal failure (ckd). they are increasingly rare because hyperparathyroidism in now diagnosed and treated at an early stage. we report 67-year-old man who had been on hemodialysis for crf for over 3 years, who presented with back pain over the thoracolumbar junction from 2 years ago and because of pain he could not ...

introduction: the aim of this study was to report surgical strategies and clinical outcomes for thoraco-lumbar intradural lipomas. intraspinal lipomas are rare congenital histologically benign neoplasms, which account for less than 1% of all spinal cord tumors. these tumors are most frequently found in the lumbosacral area as components of a dysraphic state, however, intramedullary lipomas are ...