bone loss after spinal cord injury leads to increased fragility of bone and subsequent risk for low-trauma fractures in the sublesional parts of the body . although in such injuries upper limbs are normally innervated, bone loss may occur in the upper extremities. the present study was designed to determine the systemic effects of spinal cord injury on the fracture healing of upper limbs in rab...

The pathophysiology of acute spinal cord injury (SCI) involves primary and secondary mechanisms of injury. Secondary injury mechanisms include inflammation, oxidative stress. The secondary inflammation of spinal cord tissue after SCI was critical for the survival of motor neuron and functional recovery. Flaxseed is a rich source of lignan phytoestrogen, α-linolenic acid. Flaxseed has rema...

A spinal cord injury is an uncommon discovery in a clay-shoveler’s fracture. Multiple syncope could be caused by bradycardia which followed injury. These combination findings adds its rarity. This case report aim to share awareness among physicians of the rare complication and management. descriptive also narratively review other literature. Physicians should aware SCIWORA (Spinal Cord Injury W...

Background: Oligodendrocyte cell death is among the important features of spinal cord injury, which appears within 15 min and occurs intensely for 4 h after injury, in the rat spinal contusion model. Accordingly, the number of oligodendrocytes progressively reduced within 24 h after injury. Administration of oligodendrocyte-like cells (OLCs) into the lesion area is one of the approaches to coun...

Background: Thoracolumbar spinal fractures include a range of injuries of various severities from simple apophysealfractures to neurological injury and complex fractures associated with vertebral dislocation. The treatment ofthoracolumbar fractures is challenging, especially due to the difficulty of evaluating the posterior ligamentous complex(PLC). The purpose of this study w...

objective(s): ischemia/reperfusion (i/r) injury of spinal cord is leading to the paraplegia observed. in this study, we investigated the protective effect of the saffron extract on spinal cord i/r injury. materials and methods: thirty five male sprague-dawley rats were divided into 5 groups: intact, sham surgery, normal saline (ns), low dose saffron aqua extract, high dose saffron aqua extract....

In thoracolumbar spinal fractures with posterior column injury for applying proper management, it is important to distinguish a flexion-distraction injury (FDI) from a three column burst fracture (BF) as in clinical examination, both may have a similar significant tenderness on direct spinal palpation. Careful attention to the comprehensive clinical examination and detailed imaging features are...

conclusions these results showed that the administration of sdf-1a increases the number of proliferating cells in the injured area in the spinal cord and improves functional recovery. results significant improvements in locomotor function were detected in the sdf-1 group compared with the sci and vehicle groups (p < 0.05). the results showed that sdf-1 treatment increased proliferative cells at...