A panel of seven monoclonal antibodies has been used to characterise 164 cerebral and spinal tumours. These reagents have enabled rapid and accurate diagnosis of tumours to be made, particularly in cases where standard techniques have proved equivocal. On the basis of characteristic antigenic profiles of tumours, it has been possible to distinguish between gliomas, meningiomas, schwannomas, med...

Primary spinal non-Hodgkin's lymphoma is extremely rare, and the occurrence of spinal dumbbell-shaped lymphoma is exceptional. We present a case of primary spinal dumbbell-shaped lymphoma to clarify the diagnosis and the management of these lesions. A 45-year-old man presented with sensory symptoms for 8 months. Magnetic resonance imaging of the thoracic spine demonstrated a dumbbell-shaped les...

PURPOSE To evaluate the outcome of osteoplastic laminotomy after excision of primary tumours of the thoracolumbar and lumbar spine. METHODS Records of 10 male and 11 female consecutive patients aged 15 to 57 (mean, 37) years who underwent osteoplastic laminotomy for excision of spinal cord tumours in the thoracolumbar (n=13) and lumbar (n=8) spine were reviewed. After tumour resection, the re...

OBJECTIVES
 Spinal tumours are known to be much less common compared brain neoplasms. In our setting, due poor data gathering, underreporting and probably lack of presentation medical facilities, studies on spinal sparse. Previous had reported extramedullary more in environment. This study examines the histomorphological spectrum an African comparing it with previous observations determine...

An 11-year-old spayed female Toy Poodle presented with acute tetraparesis. A small subcutaneous mass was found in the right trunk region, and magnetic resonance revealed a compressive spinal cord lesion due to an irregular bone proliferation at third cervical vertebra. After surgical resection of vertebral lesion, neurological symptoms improved, patient could walk on her own. The excised masses...

Introduction Primary CNS neoplasms represent 2% of all cancers and are the sixth most common group of tumours in adults and the second most common form of cancer in children, accounting for 20% of cancers in children under the age of 15 years. Although the incidence of tumours metastatic to the central nervous system outnumbers the combined incidence of tumours arising in the brain, spinal cord...

Although very rare, cases of cauda equina tumours migrating several levels have been known to occur. We report two cases of cauda equina schwannomas which migrated from its primary site, one caudally and the other one rostrally as confirmed by magnetic resonance imaging perioperatively. The f irst patient was a 27-year-old man and the second a 41year-old man; both presented with back pain. This...

Cranial MRI showed multiple lesions in white matter that were thought to be consistent with multiple sclerosis in two young adults presenting with symptoms of progressive myelopathy. MRI of the cervicothoracic spine around one and two years after onset showed the myelopathy to be due to mid-thoracic tumours. The tumours (an extradural meningioma and intradural neuroma) were resected with comple...

The cerebellar, retinal, and one of the spinal haemangioblastomas in a case of von Hippel-Lindau syndrome were studied by immunocytochemistry and electron microscopy. The tumours were positive for neurone specific enolase and variably positive for somatostatin, pancreatic polypeptide, and bombesin. Electron microscopy of the cerebellar tumour showed secretory granules with an average diameter o...