Long-term memory relies on modulation of synaptic connections in response to experience. This plasticity involves trafficking of AMPA receptors (AMPAR) and alteration of spine morphology. Arc, a gene induced by synaptic activity, mediates the endocytosis of AMPA receptors and is required for both long-term and homeostatic plasticity. We found that Arc increases spine density and regulates spine...

There are no two identical things in nature, as well deformities of the feet, spine. Some people like straight fingers, and some don’t. For 60 years work orthopedics, participating many international conferences, I have never heard why so bad how they can be eliminated.

We present a comprehensive analysis of the formation and evolution fan-spine-like configuration that developed over complex photospheric where dispersed negative polarity regions were surrounded by positive regions. This unique configuration, analogous to geological "atoll" shape, hosted four homologous flares within its boundary. Computation degree squashing factor (Q) maps clearly revealed an...

Cervical spine injuries are rarely seen in children with an overall incidence of about 1-1.5% [1,2]. In pediatric cervical spine injury, the upper cervical spine is the most common site affected (52% of cases) [2]. The typical injury mechanisms for pediatric cervical spine injuries are hyper flexion movements as in motor vehicle accidents, because of distinct anatomic properties of a child’s bo...

Functional consequences to which vertebrate GATA transcription factors contribute in the adult brain remain largely an open question. The present study examines how human GATA-1 and GATA-2 (hGATA-1 and hGATA-2) are linked to neuronal differentiation and depressive behaviors in rats. We investigated the effects of adeno-associated viral expression of hGATA-1 and hGATA-2 (AAV-hGATA1 and AAV-hGATA...

Percutaneous tracheostomy (PCT) is a safe method under proper patient selection, increased technical experience and bronchoscopy- or ultrasound-guided procedure. Trauma patients with cervical spine fractures and spinal cord injury are at a high risk for respiratory failure and require a definitive airway followed by prolonged mechanical ventilation. We would like to present multiple, life- thre...

Depression, a severe psychiatric disorder, has been studied for decades, but the underlying mechanisms still remain largely unknown. Depression is closely associated with alterations in dendritic spine morphology and spine density. Therefore, understanding dendritic spines is vital for uncovering the mechanisms underlying depression. Several chronic stress models, including chronic restraint st...

OBJECTIVE To compare simultaneous measurements of pulse pressure variation (PPV) and pleth variability index (PVI) in patients undergoing spinal fusion. AIMS To determine if PVI can be used as a surrogate for PPV and also the influence of the prone position on these measurements. BACKGROUND Spine fusion is an involved surgical procedure requiring attention to fluid administration. Dynamic i...

[Purpose] Low back pain is a pervasive problem in modern societies. Physical rehabilitation in treatment of low back pain should reduce pain, muscle tension and restore spine stability and balance. The INFINITY® rehabilitation method that is based on a figure of eight movement pattern was proved to be effective in low back pain treatment. The aim of the paper is to estimate the effect of a figu...