Background: Obstructive sleep apnoea and obese hypoventilation is not uncommon in patients with obesity. Residuals effect from surgery/anaesthesia and opioid analgesics may worsen respiration during the first nights after bariatric surgery. The aim of this observational study was to monitor respiration on the first postoperative night following elective bariatric surgery. Methods: This observat...

background. given the influence of systemic blood pressure on pulpal blood flow, anxiolytics prescribed may alter the pulpal blood flow along with the local anesthetic solution containing a vasoconstrictor. this study evaluated the impact of preoperative anxiolytics and vasoconstrictors in local anesthetic agents on pulpal oxygen saturation. methods. thirty anxious young healthy individuals wit...

INTRODUCTION This study investigates the relation between changes in pulse oximeter oxygen saturation (SpO2) and changes in arterial oxygen saturation (SaO2) in the critically ill, and the effects of acidosis and anaemia on precision of using pulse oximetry to predict SaO2. PATIENTS AND METHODS Forty-one consecutive patients were recruited from a nine-bed general intensive care unit into a 2-...

OBJECTIVES To investigate the severity and duration of hypoxaemia in 703 children with severe or very severe pneumonia presenting to Goroka Hospital in the Papua New Guinea highlands; to study the predictive value of clinical signs for the severity of hypoxaemia, the predictive value of transcutaneous oxygen saturation (SpO2) and other variables for mortality. DESIGN Prospective evaluation of...

In recent years, oxygen targeting has become a relevant topic in neonatal intensive care medicine.1 Despite large SpO2 targeting trials including numerous subjects and the available results of a meta-analysis of these data,2,3 there is still an ongoing debate on the optimum SpO2 target range in preterm infants. Both conditions, hyperoxia as well as hypoxia, frequently occur in extremely low bir...

Oxygen therapy is a mainstay of critical care medicine, yet its optimal therapeutic use has not been systematically evaluated. A detailed understanding of current practice in oxygen therapy in intensive care is required to enable future interventional studies. We aimed to describe current oxygenation practice in patients requiring ≥48 hours of mechanical ventilation (MV) at an academic tertiary...

We determined the effects of chronic exposure to intermittent hypoxia (CIH) on chemoreflex control of ventilation in conscious animals. Adult male Sprague-Dawley rats were exposed to CIH [nadir oxygen saturation (SpO2), 75%; 15 events/h; 10 h/day] or normoxia (NORM) for 21 days. We assessed the following responses to acute, graded hypoxia before and after exposures: ventilation (V̇e, via baromet...

Results Mean PaO2/FiO2 at baseline was 200 ± 57 mm Hg in the HFNC group and 205 ± 59 mm Hg in the BVM group (p = 0.76). Mean SpO2 at baseline was 96 ± 3 % in the HFNC group and 94 ± 4 % in the BVM group (p = 0.24). The mean lowest oxygen saturation measured by pulse oximetry (SpO2) during intubation was 89 ± 18 % in the HFNC group and 86 ± 11 % in the BVM group (p = 0.56). During the one minute...

BACKGROUND Managing the oxygen saturation of preterm infants to a target range has been the standard of care for a decade. Changes in target ranges have been shown to significantly impact mortality and morbidity. Selecting and implementing the optimal target range are complicated not only by issues of training, but also the realities of staffing levels and demands. The potential for automatic c...