Broth culture filtrates from several strains of Staphylococcus aureus produce fever when injected intravenously into normal or previously sensitized rabbits.' This response appears to depend upon a naturally acquired state of delayed hypersensitivity, which may be increased with specific infection.2 Rabbits made unreactive (tolerant) to filtrate from one staphylococcal strain were tolerant to f...

Introduction Polymyositis and dermatomyositis may be asscciated with autoimmune phenomena and with malignancy. The initiating factors are unclear; viral infections have been proposed (Pearson and Bohan, 1977) and a few cases have been associated with bacterial and parasitic infections (Naidoo and Chan, 1975; Kegen, Kimball and Christian, 1974; Greenlee et al., 1975; Samuels and Rietschel, 1976)...

Staphylococcal scalded skin syndrome (SSSS) is characterized by widespread epithelial necrosis and/or superficial blistering of the following infection some toxigenic strains Staphylococcus aureus. The disease primarily affects children under age 5 years, but it can also occur in adults. Due to recent increase reported cases SSSS, we have reviewed epidemiology, pathogenesis, clinical features, ...

Staphylococcus sp. is not only a commensal bacterium but also a major human pathogen that causes a wide range of clinical infections, such as skin and soft tissue infection, pleuropulmonary and osteoarticular infection, and endocarditis as well as lifethreatening systemic infections. More evidence is currently emerging to show that Staphylococcus, particularly Staphylococcus aureus, can coloniz...

Staphylococcus aureus is a common and often virulent pathogen in humans. This bacterium is widespread, being present on the skin and in the nose of healthy people. Staphylococcus aureus can cause infections with severe outcomes ranging from pustules to sepsis and death. The introduction of antibiotics led to a general belief that the problem of bacterial infections would be solved. Nonetheless,...

Staphylococcus aureus frequently causes community- and hospital-acquired infections. S. attachment followed by biofilm formation on tissues medical devices plays a significant role in the establishment of chronic Staphylococcal biofilms encase bacteria matrix protect cells from antimicrobials immune system, resulting infections that are highly resistant to treatment. The biology is complex vari...

Serious staphylococcal infections continue to pose therapeutic problems despite the availability of antimicrobial agents that are effective against staphylococci in vitro. Much suggests that this relates, in part, to the nature of the basic lesion in staphylococcal disease. The abscess is the hallmark of staphylococcal disease, and many therapeutic failures appear to result from the inability o...

A 6-year-old girl had a long history of severe eczema, asthma, recurrent otitis media, and staphylococcal infections with disseminated chronic skin abscesses. Immunological studies showed a neutrophil chemotaxis defect, hyperimmunoglobulinaemia E, IgE antibodies against cows' milk proteins, absence of IgM, and absence of staphylococcal haemolysins. Neutrophil phagocytic and bactericidal functio...

Backgrounds: Neutropenia can be associated with lifethreatening infections. Gram negative and staphylococcal infections are the most common pathogens. The spectrum of bacterial isolates has changed considerably over the past four decades. The objective of the present study was to evaluate the pattern of bacterial and fungal infections in neutropenic pedi-

The decreased incidence of potentially autogenous Gramnegative bacillary infections may well be unrelated to the change in ward architecture, but the criteria used to classify cross-infection meant that some of the intestinal type of infections labelled autogenous were in fact cross-infections. As expected, the incidence of definite staphylococcal autogenous infection remained substantially the...