Hashimoto’s patients have in some cases both stimulating and blocking antibodies [2, 3]. It stands to reason that if the patient is hypothyroid, then blocking antibody avidity and/ or titer would dominate irrespective of the presence of stimulating antibodies. There is a growing list of publications that show the prevalence of TSHR stimulating autoantibodies in HT patients using bioassays. Wall...

Temperature has significant influence on physio-chemical responses of all living organisms including fish. The present study was conducted to evaluate the effect of temperature on dimethoate toxicity (96 h static bioassay) to freshwater catfish Heteropneustes fossilis. Fish mortality data were recorded at 24, 48, 72 and 96 h and analysed using EPA Probit analysis, Version 1.5, software based on...

The influence of salinity on the response of the estuarine teleost, Tilapia guineensis fingerlings to acute toxic effects of inorganic nitrogen-phosphorus-potassium (NPK) (15: 15: 15) fertilizer was investigated using semi-static bioassay. The toxicity of NPK fertilizer was found to increase significantly with increase in the salinity level from 0.05 %. to 32.4 %o. The 96 hr LC50 value at salin...

In the present investigation histopathological lesions in the selected tissues such as gills, kidney and eye of the fingerlings of Cirrhinus mrigala exposed to a sublethal concentration of mercury, i.e. 240 μg/l from static bioassay have been studied. The primary gill lamellae showed degeneration in the middle and distal region. In distal region, spherical structure showing complete degeneratio...

Present study was performed to investigate the impact of sublethal concentrations of Diazinon on different behavioral aspects of Labeo rohita. LC50 of Diazinon for 96 hrs by static bioassay test was found to be 0.004ml/l. The fishes were exposed for 96 hrs. Diazinon exposure caused decrease in resting period, increase in opercular movement and air gulping, increase in jerk, threat and burst swi...

Alpha-cypermethrin, which is a synthetic pyrethroid pesticide and potential toxic pollutant, contaminating aquatic ecosystems was investigated in the present study for acute toxicity. Nile tilapia (Oreochromis niloticus) adults were selected for the bioassay experiments. The experiments were repeated three times and the 96-h LC50 value was determined for the adults. The static test method of ac...

Haematological parameters in Albino rats were altered after exposure to sodium fluoride. Static bioassay experiments were conducted to find out Lc50 with the administration of oral dose of 10.00ppm of Naf per kg of body weight to adult healthy albino rats. The experimental doses were set up for the three groups of animals each having 4 animals for 30, 60 & 90 days time interval. Blood samples w...

Aedes aegypti L. is the mosquito vector of yellow fever, dengue, zika, and chikungunya viruses. The prevention control such diseases usually rely on use chemicals, that can cause harm to human health environment. Vegetable oils with larvicidal activity are used as an alternative tool this insect. This study aimed evaluate vegetable from Caryocar coriaceum, Mauritia fIexuosa, Carapa guianensis, ...