autoimmune diseases have been described as an interesting and poorly understood group of disorders. there are many challenges in the respective scientific societies concerning the nature, causes and the therapeutic approaches of these diseases. in accordance with the evidences the nature and etiology of these disorders is multifactorial and complex but the clearest definition could be expressed...

introduction: the field of stem cell biology and regenerative medicine is rapidly moving toward translation to clinical practice. stem cell therapy seems to be a new treatment option for some diseases. so, tracking the distribution of stem cells is crucial to their therapeutic use. based on this fact we labeled human mesenchymal stem cells (mscs) with 111in- oxine for the first time in our coun...

mobile phone use and wireless communication technology have grown explosively over the past decades. this rapid growth has caused widespread global concern about the potential detrimental effects of this technology on human health. stem cells generate specialized cell types of the tissue in which they reside through normal differentiation pathways. considering the undeniable importance of stem ...

objective: this study presents an efficient, cost-effective method to improve proliferation and colonization of spermatogonial stem cells (sscs) in vitro. methods: isolated sscs from neonate mice were cultured in dmem culture medium with 10% fetal bovine serum (fbs). in the first phase of the study, the temperature was controlled by low intensity pulsed ultrasound stimulation (lipus) of the pla...

In flowering plants, haploid gametes – an egg cell and a sperm fuse to form the first diploid zygote. The zygote is progenitor stem that gives rise all embryonic post tissues organs. Unlike animals, both maternal paternal gene products participate in initial development of zygotes plants. Here, we discuss recent advances understanding zygotic transition embryo initiation angiosperms, including ...

background:   objective: this study presents an economical and simple co-culture system for pluripotent stem cells generation from neonatal mouse testis   materials and methods: isolated testicular cells were cultured in dmem/f12. characteristics of the isolated cells and obtained es-like cell were immune-cytochemically confirmed by examining the presence of plzf, vimentin, oct4 and nanog prote...

The study of cell behavior is of crucial importance in drug and disease research. The fields of bioinformatics and biotechnology rely on the collection, processing, and analysis of huge numbers of biocellular images, including cell features such as cell size, shape, and motility. However manual methods of inferring these values are so onerous that automated methods of cell tracking and segmenta...

multiple sclerosis (ms) is an inflammatory disease of the central nervous system (cns). inflammation caused by immune cells destroy the myelin and then axon. cns failure to complete repair results in permanent disabilities. some types of stem cells have special potentials to repair these injuries and even cure ms. neural crest stem cells with a mutual origin with cns and the ability of differen...

multipotent mesenchymal stromal cells or mesenchymal stem cells (mscs) are mainly isolated from bone marrow or fat tissue. because of their potential of multilineage differentiation towards bone, cartilage and fat tissue, they were initially evaluated to develop innovative strategies for tissue engineering applications. more recently, they have gained interest based on their immunomodulatory pr...

spermatogonial stem cells (sscs) maintain spermatogenesis throughout life in the male. maintenance of sscs and induction of spermiogenesis in vitro may provide a therapeutic strategy to treat male infertility. this study investigated in vitro differentiation of mouse sscs in presence or absence of sertoli cells, hormones and vitamins. spermatogonial populations were enriched from testes of 4-6 ...