نتایج جستجو برای: stem disc bulb

تعداد نتایج: 333492  

Journal: :Human molecular genetics 2009
W S Layman D P McEwen L A Beyer S R Lalani S D Fernbach E Oh A Swaroop C C Hegg Y Raphael J R Martens D M Martin

Mutations in CHD7, a chromodomain gene, are present in a majority of individuals with CHARGE syndrome, a multiple anomaly disorder characterized by ocular Coloboma, Heart defects, Atresia of the choanae, Retarded growth and development, Genital hypoplasia and Ear anomalies. The clinical features of CHARGE syndrome are highly variable and incompletely penetrant. Olfactory dysfunction is a common...

Journal: :Contrast media & molecular imaging 2014
Dimitri Roose Frederic Leroux Nathalie De Vocht Caroline Guglielmetti Isabel Pintelon Dirk Adriaensen Peter Ponsaerts Annemie Van der Linden Sara Bals

In this study, the interaction between cells and micron-sized paramagnetic iron oxide (MPIO) particles was investigated by characterizing MPIO in their original state, and after cellular uptake in vitro as well as in vivo. Moreover, MPIO in the olfactory bulb were studied 9 months after injection. Using various imaging techniques, cell-MPIO interactions were investigated with increasing spatial...

Journal: :Genes & development 2008
Michael Rendl Lisa Polak Elaine Fuchs

Hair follicle (HF) formation is initiated when epithelial stem cells receive cues from specialized mesenchymal dermal papilla (DP) cells. In culture, DP cells lose their HF-inducing properties, but during hair growth in vivo, they reside within the HF bulb and instruct surrounding epithelial progenitors to orchestrate the complex hair differentiation program. To gain insights into the molecular...

Journal: :Brain research 2009
Gaëtan J-R Delcroix Matthieu Jacquart Laurent Lemaire Laurence Sindji Florence Franconi Jean-Jacques Le Jeune Claudia N Montero-Menei

Mesenchymal stem cells (MSC) may transdifferentiate into neural cells in vitro under the influence of matrix molecules and growth factors present in neurogenic niches. However, further experiments on the behavior of such stem cells remain to be done in vivo. In this study, rat MSC (rMSC) have been grafted in a neurogenic environment of the rat brain, the subventricular zone (SVZ), in order to d...

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 2013
Nancy Lee Myra K Batt Brigitte A Cronier Michele C Jackson Jennifer L Bruno Garza Dennis S Trinh Carter O Mason Rachel P Spearry Shayon Bhattacharya Rachel Robitz Masato Nakafuku A John MacLennan

Appropriately targeted manipulation of endogenous neural stem progenitor (NSP) cells may contribute to therapies for trauma, stroke, and neurodegenerative disease. A prerequisite to such therapies is a better understanding of the mechanisms regulating adult NSP cells in vivo. Indirect data suggest that endogenous ciliary neurotrophic factor (CNTF) receptor signaling may inhibit neuronal differe...

2009
Gaëtan J-R DELCROIX Matthieu JACQUART Laurent LEMAIRE Laurence SINDJI Florence FRANCONI Jean-Jacques LE JEUNE Claudia N. MONTERO-MENEI Claudia N. Montero-Menei

Mesenchymal stem cells (MSC) may transdifferentiate into neural cells in vitro under the influence of matrix molecules and growth factors present in neurogenic niches. However, further experiments on the behavior of such stem cells remain to be done in vivo. In this study, rat MSC (rMSC) have been grafted in a neurogenic environment of the rat brain, the subventricular zone (SVZ), in order to d...

Journal: :Stem Cells and Cloning: Advances and Applications 2009

Journal: :Archives of ophthalmology 2007
Rasik B Vajpayee Namrata Sharma Vishal Jhanji Jeewan S Titiyal Radhika Tandon

OBJECTIVE To describe the use of a single donor corneal tissue in 3 patients with corneal pathologic conditions. METHODS A donor corneal tissue was divided into 3 parts using a microkeratome and a trephine. The anterior lamellar disc was transplanted into a patient with macular corneal dystrophy using the automated lamellar therapeutic keratoplasty technique. The posterior lamellar disc was t...

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