Placing a coronary stent during angioplasty minimizes reduces of acute vessel occlusion [1] and restenosis [2]. Although permanent metallic stents are effective in preventing recoil and late restenosis after coronary angioplasty, they continue to have limitations such as stent thrombosis and mismatch of the stent to the vessel size. In-stent restenosis is the major shortcoming of conventional (...

INTRODUCTION Coronary angioplasty with stenting has revolutionized the treatment of coronary artery disease. This article describes the history of coronary angioplasty and stenting, reviews the contemporary stents and recommendations and highlights the on-going work and potential future directions. SOURCES OF DATA This review examined the data on coronary stents available in PubMed. AREAS O...

Magnesium alloys have attracted considerable interest as prospective biodegradable materials in cardiovascular stents because of their metal mechanical properties and biocompatibility. However, fast degradation slow endothelialization results the premature disintegration integrity restenosis implanted Mg-based stents, which is primary hurdle limiting predicted clinical applicability. The develo...

OBJECTIVE #ENTITYSTARTX02014; This study is to explore the effect of valsartan-eluting stents on neointima formation after stenting and to elucidate possible mechanisms how locally used valsartan prevents in-stent restenosis (ISR). METHOD valsartan- and carriereluting stents were manufactured by using multi-layer-coated technology. Bare stents, carrier-eluting stents and valsartan- eluting st...

Ureteral stents are commonly used in urology. Every urologist is familiar with the problems that are associated with stents including infection, encrustation, and bothersome symptoms. These problems limit and affect the use of ureteral stents which are necessary, even in light of the problems they can cause. New designs such as a helically cut ureteral stent which is designed to stretch and con...

The use of intravascular stents may be limited by both local thrombosis and restenosis due to intimal proliferation. In an effort to provide solutions to these problems, we seeded stents with genetically engineered endothelial cells in vitro. Using retroviral-mediated gene transfer, we inserted the gene for either bacterial beta-galactosidase or human tissue-type plasminogen activator (t-PA) in...

It is not clear what effects of CD34- and CD133-specific antibody-coated stents have on re-endothelialization and in-stent restenosis (ISR) at the early phase of vascular injury. This study aims at determining the capabilities of different coatings on stents (e.g. gelatin, anti-CD133 and anti-CD34 antibodies) to promote adhesion and proliferation of endothelial progenitor cells (EPCs). The in v...

In a 27 months period from Aug. 2010 to October 2012, 189 patients (aged 35-79, mean 56.6 years, 169 males) with 318 stents subsequently underwent ICA after CTA on the same day in 182 (96.3%) patients, on the second day in 6 (3.2%), and on the 4th day in one patient (0.5%). The interval time between the last stents implantation and CTA was 3.6 to 61.6 (mean 11.2) months. Significant ISR was def...

Background—Experimental studies have demonstrated that P radioactive stents reduce neointimal formation at 28 days in porcine iliac and coronary arteries. Our objective was to determine the long-term dose-response effects of 1.0to 12.0-mCi P radioactive stents in a porcine atherosclerotic coronary model. Methods and Results—Control (n519) and 1.0to 12.0-mCi P radioactive (n543) stents (total, n...

Coronary stents are the most important supports in present day cardiology. Flexibility and trackability are two basic features of stents. In this paper, four different balloon-expandable coronary stent systems were investigated mechanically in order to compare their suitability. The coronary stent systems were assessed by measurements of stent flexibility as well as by comparison of forces duri...