Christopher A Hamm ([email protected]) Jeff W Stevens ([email protected]) Hehuang Xie ([email protected]) Elio F Vanin ([email protected]) Hakeem Abdulkawy ([email protected]) Simone T Sredni ([email protected]) Jared Bischof ([email protected]) Deli Wang ([email protected]) Sergey Malchenko (SMalchenko@childrensmemo...

THE following case is of interest in that it illustrates the effectiveness of a new penicillin derivative, ampicillin ('Penbritin') (6 D (-) o-amino-phenylacetimido penicillanic acid) which is active against a number of Gram-negative as well as Grampositive organisms. Preliminary reports on Penbritin appeared in the British Medical Journal on July 22, I96I (Rolinson and Stevens, Brown and Acred...

We present a case of Stevens Johnson syndrome in a child after carbamazepine application and Stevens Johnson/TEN overlap syndrome in an adult after amoxicillin application. On the basis of two reported cases we review the most commonly associated drugs, the postulated pathogenesis, clinical manifestation and management in these severe life-threatening diseases. We especially discuss the controv...

1.1 Skin The evolution of life in the terrestrial environment required the development of a waterproof integument: the skin (Loden and Maibach, 2006). Skin is an extensive organ covering the entire exterior of the body (Stevens and Lowe, 2005). It provides the primary barrier against chemical and biological external agents and water loss (Hadgraft, 2001). The skin also plays an important role i...

AMERICAN MEDICINE AND THiE PUBLIC INTEREST. By Rosemary Stevens. New Haven, Connecticut, Yale University Press, 1971. xiii, 572 pp. $18.50. In this second volume of a planned trilogy, Rosemary Stevens presents a sclholarly analysis of the evolution of specialization in American Medicine. In pointing out the transformation of the average doctor in a slhort span of time from relative scientific i...

We apply the Bayesian quantile regression (BayesQR) model for binary response variables and unsupervised learning methods to synthetic data (Stevens Anderson-Cook, 2017a, 2017b), which is univariate with a of passing or failing complex munitions generated match age usage rate found in US Department Defense systems (Army Navy). Instead generalised linear (GLM) used Stevens Anderson-Cook (2017a),...

Studying how individuals compare two given quantitative stimuli, say d1 and d2, is a fundamental problem. One very common way to address it is through ratio estimation, that is to ask individuals not to give values to d1 and d2, but rather to give their estimates of the ratio p = d1/d2. Several psychophysical theories (the best known being Stevens’ power-law) claim that this ratio cannot be kno...

This case report describes a 41-year-old Afro-Caribbean lady presenting with a constellation of pyrexia, conjunctivitis, arthralgia, sterile dysuria, apthous ulceration, labial crusting and widespread erythema multiforme. A diagnosis of Stevens-Johnson Syndrome was made. She had taken no medications recently (the most common precipitant of Stevens-Johnson Syndrome) and a full screen for the com...

Erythema multiforme may be placed on a disease continuum that includes Stevens-Johnson syndrome and toxic epidermal necrolysis. It was first described in 1866 by Hebra as a skin disease with symmetrically distributed red papules, evolving within several days to form annular or iris-like shapes or blisters. The term multiforme described this evolution of primary lesions into different forms. In ...

We report a case of bronchiolitis obliterans associated with Stevens-Johnson syndrome. A 59-year-old man presented with respiratory distress that gradually worsened over 3 months. He had been diagnosed with Stevens-Johnson syndrome 3 months before admission. He had no history of previous airway disease. On physical examination, expiratory breathing sounds were not audible, and a chest X-ray rev...