Long-term potentiation of human pain perception (nociceptive LTP) to single electrical test stimuli was induced by high-frequency stimulation (HFS) of cutaneous nociceptive afferents. Numerical pain ratings and a list of sensory pain descriptors disclosed the same magnitude of nociceptive LTP (23% increase for >60 min, P < 0.001), whereas affective pain descriptors were not significantly enhanc...

THERE has long been a need in ophthalmology for a pleasant, non-irritant, safe and effective local analgesic, free from such side-effects as pupil dilatation or cycloplegia. The compounds in common use to-day, such as cocaine 4 per cent. (D.D.A.), affect the pupil and desiccate the cornea, and amethocaine (Pantocain, Pontocaine, Tetracain) and related compound amylocaine (Dorsacaine, Phenolaine...

RESULTS. A total of 181 schoolchildren (0.83%) in the 3 districts were dispensed injectable epinephrine during the school year studied. Diagnoses listed for the prescription of epinephrine included peanut/tree nut allergy (65%), stinging-insect allergy (19%), seafood allergy (6%), and egg or dairy allergy (3%). A miscellaneous group (7%) included diagnoses for latex, chocolate, pollen, fruit, c...

Background: PlantCrystals are a new concept to produce plant-based formulations. Their principle is based on the diminution of parts or whole plants. In this study, effect surfactant stinging nettle leaf was investigated. Secondly, contents bulk material and formulation were compared. addition, for very first time, skin penetration Methods: Stinging leaves milled with high-pressure homogenizati...

Using an enriched library method, seven polymorphic microsatellite loci were isolated from the barley stem gall midge, Mayetiola hordei. Polymorphism at loci was surveyed on 57 individual midges collected on barley in Tunisia. Across loci, polymorphism ranged from two to six alleles per locus. The observed heterozygosity varied between 0.070 and 0.877. Based on the number of alleles detected an...

AIMS To evaluate the claim that topical proxymetacaine produces little or no discomfort on instillation by comparing it against topical amethocaine. METHODS This randomised, masked, double blind, prospective study involved 53 consecutive patients. Each patient received one drop of amethocaine 0.5% in one eye and one drop of proxymetacaine 0.5% in the other. The duration of the stinging sensat...