With the threat of significant morbidity and mortality following an influenza pandemic, stockpiling of antiviral agents such as oseltamivir is recommended. Shelf-life extension was explored to maximize use of an existing stockpile. This analysis demonstrated that oseltamivir retains potency defined by United States Pharmacopeia acceptance criteria beyond the labeled expiration date.

PT Adaro Indonesia (AI) is one of the largest thermal coal producers in with production around 40-50 million tons per year. AI’s mine business processes are managing mining operations and selling to customers. To transport from sites sales points, AI travels by land river. This paper will focus on transportation land. Land carried out Stockpile/ROM (run-of-mine) Barito River Port Kelanis Dedica...

The Comprehensive Test Ban Treaty of 1996 banned any future nuclear explosions or testing of nuclear weapons and created the CTBTO in Vienna to implement the treaty. The U.S. response to this was the cessation of all above and below ground nuclear testing. As such, all stockpile reliability assessments are now based on periodic testing of subsystems being stored in a wide variety of environment...

BACKGROUND Following successful eradication of wild polioviruses and planned globally-coordinated cessation of oral poliovirus vaccine (OPV), national and global health leaders may need to respond to outbreaks from reintroduced live polioviruses, particularly vaccine-derived polioviruses (VDPVs). Preparing outbreak response plans and assessing potential vaccine needs from an emergency stockpile...

To what extent is the observed mis-pricing in experimental asset markets caused by strategic uncertainty (SU) and by individual bounded rationality (IBR)? We address this question by comparing subjects initial price forecasts in two market environments – one with six human traders, and the other with one human and five computer traders. We find that both SU and IBR account equally for the media...

INTRODUCTION In recent years, government and hospital disaster planners have recognized the increasing importance of pharmaceutical preparedness for chemical, biological, radiological, nuclear, and explosive (CBRNE) events, as well as other public health emergencies. The development of pharmaceutical surge capacity for immediate use before support from the (US) Strategic National Stockpile (SNS...

INTRODUCTION In the event of a major chemical, biological, radiological, nuclear, or explosive (CBRNE) attack or a natural disaster, large quantities of pharmaceuticals and medical supplies may be required with little or no warning. Pharmaceutical surge capacity for immediate response, before Strategic National Stockpile (SNS) supplies become available, remains a significant gap in emergency pr...

The United States has maintained a safe, secure, and reliable nuclear stockpile for 16 years without relying on underground nuclear explosive tests. We argue that a key ingredient of this success so far has been the expertise of the scientists and engineers at the national labs with the responsibility for the nuclear arsenal and infrastructure. Furthermore for the foreseeable future this cadre ...