The aim of the present study was to define changes in the expression of somatostatin (SOM) in the sympathetic perikarya innervating the porcine stomach prepyloric area during acetylsalicylic-acid-induced gastritis (ASA) and experimentally induced hyperacidity (HCL) and following partial stomach resection (RES). On day 1, the stomachs were injected with neuronal retrograde tracer Fast Blue (FB)....

It has been reported that after treatment with atropine, stimulation of the vagus nerve causes a relaxation of the stomach which is possibly mediated by a non-adrenergic inhibitory mechanism (1-4). Biilbring and Gershon (5) proposed that 5-HT, with acetylcholine, seemed to be a neuro-transmitter substance in the vagal inhibitory pathways of the guinea-pig stomach. According to them, in the pres...

Diabetic gastroparesis (DG) is a common clinical complication of diabetes mellitus. Leptin may cause delayed gastric emptying in the central and peripheral pathways. Microcirculatory disturbances in the stomach make gastric smooth muscles and nerves hypoxic-ischemic, thereby impairing gastric motility. Irbesartan is an angiotensin II (ATII) receptor blocker that indirectly decreases serum lepti...

Background: Eucalyptus oil often used for medicinal purposes. Aims: The gastro protective impact investigated against gamma-rays-exposure-induced gastric ulceration in rats. Materials and Methods: Thirty-two rats were divided equally into 4groups; control, (100mg/ kg), gamma-rays (7Gy) plus treated groups. stomach histopathology samples examined. levels of malondialdehyde, reduced glutathione, ...

The aim of the study was to determine whether ghrelin treatment has a protective effect on gene expression and biochemical changes in the stomach of newborn streptozotocin (STZ) induced diabetic rats. In this study, four groups of Wistar rats were used: control, ghrelin control, diabetic and diabetic+ghrelin. The rats were sacrificed after four weeks of treatment for diabetes. The gene expressi...

Prior studies have demonstrated that inflammation can sensitize visceral afferent neurons, contributing to the development of hyperalgesia. We hypothesized that both afferent and efferent pathways are affected, resulting in changes in motor and sensory function. Kissing ulcers (KU) were induced in the distal stomach by injecting 60% acetic acid for 45 s into a clamped area of the stomach. In co...

A 24-year-old female with a history of major depressive disorder, borderline personality disorder, and post-traumatic stress disorder presented complaining of worsening abdominal pain over the last 48 h. She reported previously watching an episode of a television medical drama in which a patient swallowed magnets and found out this was very dangerous. She then tried this herself and swallowed m...

The potential reversibility of glandular stomach lesions induced by the clastogen, catechol, was examined in groups of male F344 rats treated continuously with 0.8% catechol in the diet for 12, 24, 48, 72, or 96 weeks. After a return to basal diet for 84, 72, 48, 24, and 0 weeks, respectively, the animals were killed for histopathological examination. Incidences of submucosal hyperplasia, adeno...

Purpose: We report bilateral, diffuse, uveal melanocytic proliferation caused by a stomach adenocarcinoma.Case summary: A 78-year-old male complained of visual impairment 3 months in duration. He had diabetes and undergone cataract surgery on both eyes 4 years prior. His best-corrected acuity was counting fingers the right eye 20/160 left eye. Both intraocular pressures were normal. The anterio...