Testicular varicocele, a dilation of the veins of the pampiniform plexus thought to increase testicular temperature via venous congestion, is commonly associated with male infertility. Significant study has clarified the negative impact of varicocele on semen parameters and more recent work has shed light on its detrimental effects on the molecular and ultrastructural features of sperm and the ...

Background: To compare the c l in ica l e f fec t o f varicocelectomy treatment between patients who were diagnosed as secondary varicocele caused by nutcracker syndrome (NCS) and primary varicocele patients. Methods: The secondary varicocele patients combined with NCS admitted in our hospital were systematically reviewed. All these patients had no obvious related symptoms such as gross hematur...

BACKGROUND The role of seminal colonization of Ureaplasma urealyticum in varicocele-related infertility was investigated. METHODOLOGY Semen samples were obtained from infertile patients with or without varicocele and healthy controls and were subjected to routine semen analysis and PCR. DNA was extracted by Cadieux method and analyzed by PCR protocol with species-specific primers for U. ureal...

IN the management of varicocele fertility is the overriding consideration. For the adult the concern is typically immediate, whereas for the adolescent preservation of future fertility is the primary objective. This fundamental difference largely determines the manner in which varicocele is managed. In the adult population prospective, observational management is uncommon. The majority of varic...

Objectives Varicocele is an abnormal dilation in the testicular vein, which can cause hypoxia, reactive oxygen species accumulation, elevation in testicular temperature, and promote apoptosis and increase proinflammatory cytokine production. According to the varicocele pathophysiology, it is possible that a group of cytosolic receptors called nucleotide oligomerization domain (NOD)-like recepto...

OBJECTIVES Several researchers have reported the relationship between infertility in male and varicocele for so many years but the implication of varicocele in female patients is remains elusive. Here, we aim to examine the effects of unilateral varicose ovarian vein on antioxidant capacity and oocyte quality of rat ovary after the experimental creation of varicocele in female rats. MATERIALS...

Due to the biochemical complexity of seminal fluid, we attempt to study the possible correlation between fructose, which is secreted under the effect of androgen hormone, and autoimmunity, which might play a role in varicocele associated infertility, in reducing sperm motility. Seminal fructose, antisperm antibodies (ASAs) and blood steroids hormones (testosterone and progesterone) levels were ...

Background This study was designed to create an experimental varicocele model by a simple surgical procedure in dog with minimum invasion and to investigate the effect of varicocele-induced infertility on the expression of six related genes (HSP90, HSP70, IL- 4, TNF, KITLG and KIT receptor). MATERIALS AND METHODS In this experimental study, the proximal part of the pampiniform plexus of dog t...

BACKGROUND/AIMS The aim of this study was to elucidate the usefulness of platelet indices, mean platelet volume (MPV), platelet distribution width (PDW), and platelet count in diagnosis and monitoring of varicocele. METHODS The current study included 525 patients and 379 healthy subjects from five eligible studies. We performed meta-analysis of MPV, PDW, and platelet count and mean difference...

reviewed the evolution of diagnostic methods for varicocele identification. 2 The authors discussed the subjective nature of the clinical examination and the marked inter-observer variability in varicocele grading. Although physical examination still represents the gold standard for diagnosing clinically significant varicoceles, which are those with a clear indication for repair, the aforementi...