PURPOSE To investigate whether corneal graft survival could be improved by topical or subconjunctival bevacizumab in a murine model of vascularized high-risk corneal transplantation. METHODS Before corneal transplantation, intrastromal sutures were placed for 2 weeks in the corneas of BALB/c mice, inducing intense angiogenesis. Allogeneic corneal transplantation was performed using C57BL/6 do...

background: to compare the efficacy of subconjunctival administration of bevacizumab and different doses of sunitinib malate in reducing corneal neovascularization (cnv). materials and methods: in this experimental study, central corneal cauterization was created in the right eye of fifty male sprague–dawley rats. on day 1 (1 week after cauterization), rats were randomly assigned into five trea...

the authors have reported five cases 01 subconjunctival luxation of the crystalline lens.

• Position the patient lying comfortably with his/her head supported on a pillow. • Reassure the patient that adequate anaesthetic drops will be instilled before the injection is given. • Instill anaesthetic drops at five-minute intervals over half an hour – a minimum of six drops. • Away from the patient’s view, draw up the prescribed medication using the 21G needle (Figure 1). • Change to the...

An 18-year-old man presented with severe right eyeball pain after an accidental injury via a compressed air tube. Severe eyeball pain along with tearing and photophobia were noted immediately after the compressed air injury. Ophthalmic examinations showed conjunctival injections (Fig. 1) without obvious corneal wound, foreign materials or increase in intraocular pressure (IOP). Orbital computed...

A 23-year-old man presented to La Paz Hospital complaining of a “worm moving in his eye.” He was otherwise healthy. On examination under natural light a mobile worm was seen in the superior subconjunctival space. When exposed to the bright light/heat of the slit lamp it migrated to the fornix; moments later the worm was visible again and every time it was exposed to the light it would disappear...

BACKGROUND Epithelial and fibrous downgrowths result from persistently leaky wounds with conjunctival or corneal epithelium and fibroblasts growing over corneal endothelium, iris and angle structures, leading to corneal edema and difficult-to-control glaucoma. Therapies have included en bloc resection, cryotherapy, endolaser or external photocoagulation and either 5-fluorouracil or mitomycin C ...

Traumatic subconjunctival dislocation of the posterior chamber intraocular lens (PCIOL) is a rare and emergency condition. Here, we report an interesting variation of rare case of inferior subconjuctival dislocation of PCIOL in a 75-year-old female patient following blunt trauma to her right eye with cow's head. All the previous literature with subconjuctival dislocation of PCIOL has reported t...

PURPOSE The purpose of this study was to investigate the myotoxicity of bevacizumab on extraocular muscles in a rabbit model. METHODS Thirty New Zealand white rabbits were used for this study. The animals were evenly divided into two groups. In the first group, 15 rabbits were treated with intramuscular injections of bevacizumab (1.25 mg/0.05 mL) in the right superior rectus muscle and normal...