in this paper we propose a new method for classification of subjects into schizophrenia and control groups using functional magnetic resonance imaging (fmri) data. in the preprocessing step, the number of fmri time points is reduced using principal component analysis (pca). then, independent component analysis (ica) is used for further data analysis. it estimates independent components (ics) of...

The Bradley-Terry-Luce (BTL) model for paired comparison data is able to obtain a ranking of the objects that are compared pairwise by subjects. The task of each subject is to make preference decisions in favor of one of the objects. This decision is binary when subjects prefer either the first object or the second object, but can also be ordinal when subjects make their decisions on a Likert s...

To determine the developmental stages at which positive selection can act to produce mature T cells, CD4+8+3lo thymocytes of large dividing type and of small nondividing type were sorted and transferred into the thymus of nonirradiated Thy-1 congenic recipient mice. In contrast to earlier studies, the small as well as the large thymocytes produced mature CD4+8-3hi and CD4-8+3hi progeny, althoug...

Laboratorio di Ecologia Applicata, Dipartimento Ar.Bo.Pa.Ve., Facoltà di Agraria, Università degli Studi di Napoli Federico II, Portici (Napoli), Italy, School of Biological Sciences, University of Bristol, Bristol, UK, Department of Biology, University of Madeira, Campus da Penteada, Funchal, Portugal, Forestry and Conservation, Via Botticelli, Cassino (Frosinone), Italy and Faculty of Science...

The assumption that pleiotropic mutations are more deleterious than mutations with more restricted phenotypic effects is an important premise in models of evolution. However, empirical evidence supporting this assumption is limited. Here, we estimated the strength of stabilizing selection on mutations affecting gene expression in male Drosophila serrata. We estimated the mutational variance (VM...

Background Non-book materials have unique characteristics in subject analysis that influence their information retrieval process. It is obvious that online search studies intended for books are not appropriate for music materials. There are not enough empirical studies based on what objects focus on music materials. This study aims to explore useful tools for subject search of music scores in o...

randomization is an essential component of sound clinical trials which prevents selection biases and helps in blinding the allocations. randomization is a process by which subsequent subjects enrolled into trial groups only by chance which is essentially eliminates selection biases. a serious consequence of randomization is severe imbalance among treatment groups with respect to some prognostic...

Migration tends to oppose the effects of divergent natural selection among populations. Numerous theoretical and empirical studies have demonstrated that this migration-selection balance constrains genetic divergence among populations. In contrast, relatively few studies have examined immigration's effects on fitness and natural selection within recipient populations. By constraining local adap...

In this paper we propose a feature selection method that uses the mutual information (MI) measure on a Principal Component Analysis (PCA) based decomposition. PCA finds a linear projection of the data in a non-supervised way, which preserves the larger variance components of the data under the reconstruction error criterion. Previous works suggest that using the MI among the PCA projected data ...