The neuropeptide S (NPS) and its receptor NPSR represent a transmitter system critically involved in the modulation of anxiety and arousal in rodents. Initial human studies indicate that the T-allele of the functional NPSR gene (NPSR1) polymorphism (rs324981), which increases NPS potency at NPSR, is associated with anxiety-related phenotypes. Since stress is critically involved in the pathogene...

The subjective experience of anxiety plays a central role in cognitive behavioral models of social anxiety disorder (SAD). However, much remains to be learned about the temporal dynamics of anxiety elicited by feared social situations. The aims of the current study were: (1) to compare anxiety trajectories during a speech task in individuals with SAD (n=135) versus healthy controls (HCs; n=47),...

The present study investigated whether perceived partner responsiveness—the extent to which individuals feel cared for, understood, and validated by their partner—predicted subjective sleep problems and objective (actigraph-based) sleep efficiency through lower anxiety and depression symptoms. A life span sample of 698 married or cohabiting adults (35–86 years old) completed measures of perceiv...

Background: There is increased focus on early diagnosis of dementia, and subjective awareness of memory impairment is often assumed to be an early symptom of dementia. Subjective memory impairment (SMI) is used to describe subjective awareness of memory problems in the elderly after identifiable diseases which include this symptom are excluded. The aim of the present cross-sectional study was t...

OBJECTIVE The main goal of this study has been to increase the quality of life in people of over 60 years through a positive psychology intervention. METHOD We employed a program which consists of training based on autobiographical memory, forgiveness and gratitude. The sample consisted of 46 participants aged 60-93 years. State and trait anxiety, depression, general memory, specific memories...

Personality dimensions capturing individual differences in behavior, cognition, and affect have been described in several species, including humans, chimpanzees, and orangutans. However, comparisons between species are limited by the use of different questionnaires. We asked raters to assess free-ranging rhesus macaques at two time points on personality and subjective well-being questionnaires ...

We examined the reported subjective level of pleasure and anxiety usually perceived during the four phases of the sexual sequence by 18 dispermic patients and 18 normal subjects. Relevant differences exist between the two groups in their perception of both emotions. The role of pleasure and anxiety in modulating some reflexive biological responses of the sexual sequence is discussed.

A patient-recorded audio-tape of intrusive ideation was employed as the anxiety evoking stimulus during the course of exposure therapy with an obsessional neurotic. Detailed records of the patient's subjective anxiety within and across treatment sessions documented the remission of self-reports of obsessional ideation. Treatment gains were maintained at 1-year follow-up.

OBJECTIVE The nature of the relationship between physiological and subjective responses in phobic subjects remains unclear. Phobics have been thought to be characterized by a heightened physiological response (physiological perspective) or by a heightened perception of a normal physiological response (psychological perspective). METHOD In this study, we examined subjective measures of anxiety...

background: masticatory ability as a subjective response to masticatory function indicates patients’ perception of their mastication. to the best of our knowledge, there has been no study on association between masticatory ability and psychological status. this study investigated the association between self-assessed masticatory ability (sama) and psychological status among a large sample of ir...