In subjects with Down syndrome the obstructive sleep apnea is the cause of many disorders (cognitive and cardiovascular disorders, premature exhaustion, increase of daytime sleepiness). The standard treatment in the obstructive sleep apnea is continuous positive airway pressure, which eliminates the respiratory events, allows recovery of a satisfactory quality of sleep, and suppresses daytime s...

objective: to compare the effects of aerobic and stretching exercises on severity of primary dysmenorrhea. materials and methods: this randomized clinical trial was conducted on 105 female students who were suffering from primary dysmenorrhea. the participants were divided into aerobic exercise, stretching exercise, and control groups. the two intervention groups did the exercises three times a...

The cardiovascular response to exercise in heart transplant recipients (HTR) has been compared with that of healthy individuals matched to the recipient age (RM controls). However, no study has compared HTR with donor age-matched (DM) controls. Moreover, the cardiovascular response to sustained submaximal exercise in HTR requires further evaluation. We therefore examined cardiovascular response...

The effect of heat acclimatization on aerobic exercise tolerance in the heat and on subsequent sprint exercise performance was investigated. Before (UN) and after (ACC) 8 days of heat acclimatization, 10 male subjects performed a heat-exercise test (HET) consisting of 6 h of intermittent submaximal [50% of the maximal O2 uptake] exercise in the heat (39.7 degrees C dB, 31.0% relative humidity)....

PURPOSE To investigate the magnitude and the time course of changes in endurance capacity during the first year of an aerobic endurance training program with constant HR prescription. METHODS Eighteen previously untrained subjects (7 males and 11 females, 42 +/- 5 yr, BMI of 24.3 +/- 2.5 kg x m(-2), and maximal oxygen uptake (VO(2max)) of 37.7 +/- 4.6 mL x min(-1) x kg(-1)) completed a 12-mon...

Ten physically active subjects underwent two cycling exercise trials. In the first, aerobic capacity (VO2max) was determined and the second was a 45 min submaximal exercise test. Urine samples were collected separately the day before (day 1) , the day of (day 2), and the day after (day 3) the submaximal exercise test (12 samples per subject). Metabolomic profiling of the samples was carried out...

Introduction: Exercise training increases skeletal muscle capillary density, but the molecular mechanisms of this process are not yet clear. The aim of the present study was to investigate the effect of acute long- term submaximal exercise on serum vascular endothelial growth factor (VEGF) as the main angiogenic factor, and matrix metalloproteinases 2 and 9 ( MMP-2 and MMP-9), as the degradi...

BACKGROUND Exercise intolerance is prevalent in individuals with Turner Syndrome (TS). We recently demonstrated that girls with TS have normal aerobic but altered skeletal muscle anaerobic metabolism compared to healthy controls (HC). The purpose of this study was to compare peripheral skeletal muscle microvascular function in girls with TS to HC after exercise. We hypothesized that girls with ...