Knowledge about the skin mechanical properties is essential in several domains, particularly for clinical applications and cosmetic industry. It can help to evaluate skin disease. The complex structure of the skin leads to complex mechanical behaviour [1, 2, 3]. The aim of this study was to measure the mechanical properties of the skin in the different directions and regions. The ethical and im...

It was most unfortunate that, because of the minimal risk of producing a tumour at the site of injection, the use of intramuscular iron-dextran complex, used for some time as an effective prophylactic against late anaemia of prematurity, had to be discontinued. A single injection had a long term effect and avoided the need for daily oral iron. Thus it became necessary to determine if oral treat...

The growth of Treponema denticola in a complex medium was stimulated by human ceruloplasmin and, to a lesser extent, albumin, alpha-1-antitrypsin, alpha-1-acid glycoprotein, and alpha-2-macroglobulin. Human ceruloplasmin could stimulate growth of T. denticola as well as or better than 5% rabbit serum, with a dose-response relationship of between 1 and 5 mg of ceruloplasmin per ml of culture med...

In 2003 the endless list of LATEX packages was enriched by the package pict2e, intended to substitute for the dummy one that has accompanied every LATEX distribution since 1994. This package implements everything as stated by Lamport in the second edition of his LATEX manual (for LATEX2ε). But if you explore the inner workings of the new pict2e, you discover the new package has some unexpected ...

A new nosologic vascular pattern that is defined by chronic cerebrospinal venous insufficiency (CCSVI) has been strongly associated with multiple sclerosis. The picture is characterized by significant obstacles of the main extracranial cerebrospinal veins, the jugular and the azygous system, and by the opening of substitute circles. The significance of collateral circle is still neglected. To t...

In a companion paper, we showed that weak and strong notions of substitutes in economies with discrete goods have different implications for auction theory and equilibrium theory. In contrast, for the divisible goods case with concave valuations, natural extensions of these concepts coincide. Concave substitute valuations are characterized by submodularity of the dual profit function over nonli...

Mammalian physiology is governed by a complex circadian timing system that involves interacting positive and negative transcriptional feedback loops. A key role in this feedback loop was attributed to the PAS domain helix-loop-helix protein CLOCK, on the basis of a dominant-negative mutation in this transcription factor. However, recent experiments by Reppert and coworkers with Clock knockout m...

In order to explore the impact of a degraded semantic system on the structure of language production, we analysed transcripts from autobiographical memory interviews to identify naturally-occurring speech errors by eight patients with semantic dementia (SD) and eight age-matched normal speakers. Relative to controls, patients were significantly more likely to (a) substitute and omit open class ...