نتایج جستجو برای: subutex

تعداد نتایج: 113  

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2005
Martin H Cohen John R Johnson Richard Pazdur

On March 15, 2005, the U.S. Food and Drug Administration approved temozolomide (Temodar capsules, Schering-Plough Research Institute) for the treatment of adult patients with newly diagnosed glioblastoma multiforme concomitantly with radiotherapy and then as maintenance treatment. Five hundred seventy-three glioblastoma multiforme patients were randomized to receive either temozolomide + radiot...

Journal: :The Biochemical journal 1987
M L Reeves B K Leigh P J England

Four cyclic nucleotide phosphodiesterase (PDE) activities were separated from low-speed supernatants of homogenates of human cardiac ventricle by DEAE-Sepharose chromatography, and designated PDE I-PDE IV in order of elution with an increasing salt gradient. PDE I was a Ca2+/calmodulin-stimulated activity, and PDE II was an activity with a high Km for cyclic AMP which was stimulated by low conc...

Journal: :Acta medica Iranica 2013
Seyed Mohammad Jalil Abrisham Mohammad Reza Hajiesmaeili Hossein Soleimani Hamid Pahlavanhosseini

Core decompression (CD) of the femoral head is one of the effective treatments of avascular necrosis (AVN), especially in the early stages of the disease. To investigate further the value of CD in treating the AVN, this study was performed on patients with symptomatic AVN with different etiologies who were treated with CD. This study was carried out on 25 patients (with the total number of 37 f...

Journal: :Journal of epidemiology and community health 2017
Mariana Carrera Niels Skipper

BACKGROUND Little is known about the treatments physicians choose for themselves compared with how they treat their patients. We determine if physicians prescribe different treatments to patients than to themselves. METHODS Population-based cohort study from 2004 to 2012 examining prescription claims of all Danish primary care physicians (PCP; n=3088) and all other Danish adults (n=2 334 590)...

Journal: :Theriogenology 2011
R C Rossetti A Perdigão F S Mesquita M Sá Filho G P Nogueira R Machado C M B Membrive M Binelli

The objective was to compare pharmacological strategies aiming to inhibit prostaglandin F2 alpha (PGF(2α)) synthesis (flunixin meglumine; FM), stimulate growth of the conceptus (recombinant bovine somatotropin; bST) and progesterone (P(4)) synthesis (human chorionic gonadotropin; hCG), as well as their combinations, regarding their ability to improve pregnancy rates in beef cattle. Lactating Ne...

2010

INTENDED USE The SERATEC ® Drug Screen BUP is a lateral flow, one-step immunoassay for the qualitative detection of Buprenorphine in human urine at a cut-off of 10 ng/ml. This product is used to obtain a visual, qualitative result and is intended for professional use. The assay should not be used without proper supervision and is not intended for over the counter sale to lay persons. This assay...

2013
Alex Thompson Sandie Reader Emma Field Adrian Shephard

BACKGROUND Acute sore throat (pharyngitis) is one of the most common illnesses for which children are seen by primary care physicians. Most cases are caused by viruses and are benign and self-limiting. Clinically proven, over-the-counter throat lozenges provide rapid and effective relief of acute sore throat symptoms, and are increasingly important in self-management of this condition. OBJECT...

Journal: :The Lancet. Oncology 2009
Roger Stupp Monika E Hegi Warren P Mason Martin J van den Bent Martin J B Taphoorn Robert C Janzer Samuel K Ludwin Anouk Allgeier Barbara Fisher Karl Belanger Peter Hau Alba A Brandes Johanna Gijtenbeek Christine Marosi Charles J Vecht Karima Mokhtari Pieter Wesseling Salvador Villa Elizabeth Eisenhauer Thierry Gorlia Michael Weller Denis Lacombe J Gregory Cairncross René-Olivier Mirimanoff

BACKGROUND In 2004, a randomised phase III trial by the European Organisation for Research and Treatment of Cancer (EORTC) and National Cancer Institute of Canada Clinical Trials Group (NCIC) reported improved median and 2-year survival for patients with glioblastoma treated with concomitant and adjuvant temozolomide and radiotherapy. We report the final results with a median follow-up of more ...

2012

Mechanism of Action: 1,2,3,4, : Incretins, such as glucagon-like peptide-1 (GLP-1), enhance glucose-dependent insulin secretion and exhibit other antihyperglycemic actions following their release into the circulation from the gut. Exenatide extended-release is a GLP-1 receptor agonist that enhances glucose-dependent insulin secretion by the pancreatic beta-cell, suppresses inappropriately eleva...

2010
Mari Fujimoto Kiyoshi Mihara James A. Jorgenson Kuniko Otsuka Masaki Aburada Tomie Kawada Junko Ishizaki Ken-ichi Miyamoto Makoto Otsuka

Dissolution testing is useful for controlling the quality of an oral generic equivalent (GE) drug and rejecting a bioinequivalent GE. However, several sources of variability in dissolution tests can affect evaluations of drug quality. Recently, we reported that shifting the paddle shaft off-center significantly changed the dissolution rate of sodium diclofenac tablets, with the result that some...

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