Two objectives of this study were to investigate the weekly change in plasma L-carnitine concentration during the 28 day suckling period and to determine the relative mRNA expression level of a L-carnitine transporter, OCTN2, in porcine mammary tissue at early and peak lactation. The results showed that the L-carnitine concentration of piglets after giving birth was 3.94±0.13 mg/L. L-carnitine ...

Prion diseases are a family of neurodegenerative zoonotic foodborne disorders. Although prions can be transmitted orally, the mechanism by which prions are incorporated into the intestine remains unclear. Our previous studies have shown that an abnormal isoform of prion protein (PrP(Sc)), which is the main component of prions, was efficiently incorporated into the intestine in suckling mice but...

Aim: The aim was to find out the influence of suckling and non-suckling system of rearing on growth performance of indigenous Tharparkar calves. Materials and Methods: A total of 14 Tharparkar calves was randomly divided into two groups. The Group 1 (G-1) was suckling group, in which calves were allowed to suckle from the same dam twice a day before/after milking from birth to 90 days of age, w...

To date few studies have addressed the development and function of the porcine gastric mucosal immune system and this is a major limitation to understanding the immunopathogenesis of infections occurring in young pigs. The polymeric immunoglobulin receptor (pIgR) mediates the transport of secretory immunoglobulins until luminal surface of the gut mucosa and the aim of this study was to investig...

Intestinal amino acid (AA) transport is critical for the supply of AA to other tissues. Few studies regarding AA intestinal transport systems during the period from postnatal intense development of piglets until weaning are available. In the present study, we measured the intestinal expression of b(0,+)AT according to developmental stage using the suckling Huanjiang piglet model, and documented...

Inhibition of gluconeogenesis with 3-mercaptopicolinate in suckling newborn rats caused a fall in blood [glucose], but no change in their high plasma [free fatty acid] and blood [ketone bodies]. Active gluconeogenesis seems to be more important than sparing of glucose by high concentrations of fat-derived substrates for the maintenance of normal blood [glucose] in suckling newborn rats.

Inhibition of fatty acid oxidation with pent-4-enoate in suckling newborn rats caused a fall in blood [glucose] and blood [ketone bodies] and inhibition of gluconeogenesis from lactate. Glucose utilization was not increased in newborn rats injected with pent-4-enoate. Active fatty acid oxidation appears to be essential to support gluconeogenesis and to maintain normal blood [glucose] in sucklin...

Our objective was to determine if suckling neonatal piglets are susceptible to enterohemorrhagic Escherichia coli (EHEC) O157:H7 disease. Surprisingly, EHEC O157:H7 caused more-rapid and more-severe neurological disease in suckling neonates than in those fed an artificial diet. Shiga toxin-negative O157:H7 did not cause neurological disease but colonized and caused attaching-and-effacing intest...

The developmental pattern of the branched-chain 2-oxo acid dehydrogenase complex was examined in the liver and heart of the rat throughout the suckling period. Basal activity and total activity of the complex were measured as a function of age. The hepatic enzyme activity increased dramatically and was 100% active (dephosphorylated) during the suckling period. The level of protein kinase associ...

Brahman cows were used to evaluate the effects of postpartum nutrition and suckling on reproductive and calf performance. Cows received high or low TDN and once-daily or unrestricted suckling. High TDN (H; 111% of NRC recommendation) cows received a 75% corn: 25% soybean meal diet. Low TDN (L; 93% of NRC recommendation) cows received no concentrates. Once-daily suckled (restricted, R) cows nurs...