A negative value for Tmp-aminobippurate was observed in a patient with sulfathiazole intoxication following 4 days of anuria and 5 days of marked oliguria. This negative Tmps is interpreted as indicating not only that the tubule cells had lost their ability to excrete PAH but that a portion of the PAH filtered by the glomeruli was escaping from the tubular urine by back-diffusion. It is the pur...

It has been demonstrated that the inhala­ tion of cigarette smoke produces definite alterations (widening) of the normal angio­ scotoma. This change was attributed to the nicotine in the tobacco, since the inhalation of tobacco of low nicotine content was shown to effect little if any change in the angioscotomas. Pick and Una have recently brought attention to the blockage of the nicotine ac­ t...

Kinetic Monte Carlo modeling was employed to investigate the kinetics and photodecomposition mechanism of sulfamethazine, ciprofloxacin, sulfathiazole, amoxicillin antibiotics by photo-Fenton process (iron(III) citrate/hydrogen peroxide in presence UV irradiation). The reaction kinetic mechanisms each degradation mentioned above have been achieved. rate constants values for step (including anti...

my suggestion she was treated with nicotinic acid, which resulted in complete restoration of her sight. In March 1944 Hollis and' Baty (New England) reported a case of a 6 weeks' old child treated with sulphathiazole for meningitis due to the colon bacillus. The drug sterilized the cerebro-spinal fluid in a week but left the child totally blind. The report of Hollis and Baty's case reached me b...

The minimal inhibitory concentration (MIC) values of sulfadiazine, penicillin, and rifampin for meningococcal strains isolated from civilians during 1970 were compared. The strains were isolated from various sources and geographical areas and represented several serogroups. The ranges of MIC values were as follows: 0.05 to 20 mg/100 ml for sulfadiazine, 0.01 to 0.4 mug/ml for penicillin, and 0....