In rodents, as in other species, regions of secondary somatosensory cortex (SII) may be distinguished from primary cortex (SI) both anatomically and electrophysiologically. However, the number of rodent SII sub-regions, their somatotopic organization, and their function are poorly understood. The presence of multisensory responsive neurons in some areas of SII suggests that one of its roles may...

This study explored the relationship between pretreatment systemic immune-inflammation index (SII) and overall survival (OS) in gastric cancer (GC) patients. A literature search was performed to find out articles that estimated of SII with specific clinical parameters OS GC Nine (including 10 studies) were included. total 3,850 cases eventually In patients, there no association gender (OR=0.991...

BACKGROUND Hypertension is a major public health issue worldwide, but knowledge is scarce about its patterns and its relationship to multiple axes of social disadvantages in Latin American countries. This study describes the educational inequality in the prevalence of hypertension in Brazil, including a joint stratification by gender and race. METHODS We analyzed interview-based data and bloo...

SII-K1 is a member of the transcription elongation factor S-II family. In the mouse, SII-K1 is expressed exclusively in the liver, kidney, heart, and skeletal muscle. Here, we report that deletion of the SII-K1 gene in mice resulted in the downregulation of the synaptotagmin-like 1 (Sytl 1) gene in liver and of the coiled-coil domain-containing 21 (Ccdc21) gene in liver and kidney. Moreover, th...

The primary (SI) and secondary (SII) somatosensory cortices have been shown to participate in human pain processing. However, in humans it is unclear how SI and SII contribute to the encoding of nociceptive stimulus intensity. Using magnetoencephalography (MEG) we recorded responses in SI and SII in eight healthy humans to four different intensities of selectively nociceptive laser stimuli deli...

Abstract Introduction This investigation aimed to evaluate the predictive value of systemic immune-inflammation index (SII) for in-hospital and long-term mortality in elderly patients with non-ST elevation myocardial infarction (NSTEMI). Methods In this retrospective investigation, 314 consecutive who were diagnosed NSTEMI a tertiary center included. The SII was computed as neutrophils x platel...

Combined retrograde transport-immunocytochemical experiments were carried out on cats to study the morphology, laminar distribution, and percentages of corticocortical projecting neurons of somatosensory area I (SI) and II (SII) showing immunoreactivity to an antiserum raised against the amino acid glutamate (Glu). A previously characterized anti-Glu serum (Conti et al., 1987a, b; Hepler et al....

Cellular mechanisms underlying synaptic plasticity are in line with the Hebbian concept. In contrast, data linking Hebbian learning to altered perception are rare. Combining functional magnetic resonance imaging with psychophysical tests, we studied cortical reorganization in primary and secondary somatosensory cortex (SI and SII) and the resulting changes of tactile perception before and after...