BACKGROUND Due to the increase of solar ultraviolet radiation (UV) incidence over the last few decades, the use of sunscreen has been widely adopted for skin protection. However, considering the high efficiency of sunlight-induced DNA lesions, it is critical to improve upon the current approaches that are used to evaluate protection factors. An alternative approach to evaluate the photoprotecti...

The evaluation of UV-filter in vitro percutaneous absorption allows the estimation of the systemic exposure dose (SED) and the margin of safety (MoS) of sunscreen products. As both the vehicle and pattern of application may affect sunscreen safety and efficacy, we evaluated in vitro release and skin permeation of two widely used UV-filters, octylmethoxycinnamate (OMC) and butylmethoxydibenzoylm...

Correction for ‘Nanofibrous sunscreen’ by Byeongjun Lee et al. , J. Mater. Chem. C 2022, https://doi.org/10.1039/d2tc00933a.

We have applied a PCR-based methodology to study the DNA damage induced by UV-A, UV-B and sunlight itself. Our results, employing a cell-free system, indicate that UV-B (310 nm) is approximately 30-fold more potent at inhibiting DNA synthesis than UV-A (365 nm). We were also able to show that 20 min of sunlight exposure on a summer day induced DNA damage capable of inhibiting DNA synthesis. Hen...

BACKGROUND Meta-analyses of observational case-control studies have demonstrated no association between sunscreen use and the development of malignant melanoma. OBJECTIVES To examine whether this observation is to be expected given the period during which the case-control studies were conducted, the sunscreens prevalent at that time, and how sunscreen is used and applied in practice. To predi...

OBJECTIVE An analysis of Canadian survey data was performed to identify independent predictors of different protective behaviours and of their use in combination. METHODS Data from light-skinned respondents of the 1996 National Survey on Sun Exposure & Protective Behaviours who spent 30+ minutes per day of their leisure time in the sun (N = 1,027) were analyzed. Multivariable logistic regress...

Sunscreen is a preparation that used on the surface of skin works to absorb, scatter or reflect ultraviolet light. Therefore, it necessary use ingredients become active in sunscreen. The research objectives are (a) To determine total flavonoid content and polyphenol avocado peel extract (Persea americana Mill.). (b) Knowing sunscreen activity This type exploratory experimental based quantitativ...

Sunscreens are known to protect against sunlight-induced erythema and sunburn, but their efficiency at protecting against skin cancer is still a matter of debate. Specifically, the capacity of sunscreens to prevent or reduce tissue and DNA damage has not been thoroughly investigated. The present study was undertaken to assess the ability of a chemical broad-spectrum sunscreen to protect human s...

The aim of this study was to apply multifailure survival methods to analyze time to multiple occurrences of basal cell carcinoma (BCC). Data from 4.5 years of follow-up in a randomized controlled trial, the Nambour Skin Cancer Prevention Trial (1992-1996), to evaluate skin cancer prevention were used to assess the influence of sunscreen application on the time to first BCC and the time to subse...