Abstract: Background: Trigonella foenum-graecum L (Fenugreek) is an annual herb, mainly cultivated for its seed as well sprouts. Pharmacological investigations reported anti-bacterial, anti-diabetic, anti-cancer, anti-diarrheal, anti-hypercholesteremic, and antiinflammatory activities of L. Aim: The purpose this study was to accentuate on formulation granules investigate the effect germinated (...

trichomoniasis, the most widespread sexually transmitted disease is caused by trichomonas vaginalis. this parasite is site specific for the genitourinary tract and recruitment of macrophages as well as polymorphonuclear nutrophils (pmn) to the site of infection is the first line of defense as a component of non-specific resistance and immunity. in this study, balb/c mice were infected with 10 i...

Orally disintegrating tablets (ODTs) are capable of turning quickly into a liquid dosage form in contact with the saliva, thus possessing the advantages of both the solid dosage forms particularly stability and liquid dosage forms specially ease of swallowing and pre-gastric absorption of drug. The aim of this study was to prepare a novel matrix-type buccal fast disintegrating ibuprofen tablet ...

Fast disintegrating tablets (FDTs) have received ever-increasing demand during the last decade, and the field has become a rapidly growing area in the pharmaceutical industry. Upon introduction into the mouth, these tablets dissolve or disintegrate in the mouth in the absence of additional water for easy administration of active pharmaceutical ingredients. The popularity and usefulness of the f...

The present work was carried out to formulate and evaluate immediate release tablets of Inosine Acedoben Dimepranol (IAD). Tablets were prepared by wet granulation process overcome the poor compression properties IAD powder produce high-dose tablets. Various type binders disintegrants like Povidone K-30, K-25, wheat starch, mannitol used prepare some series Granules evaluated for pre-compressio...

Tablets with 250 mg of Rhodiola rosea L. extract disintegrating in less than 10 min were developed. The influence of the extract content and type of fillers and disintegrants on disintegration time and tablet hardness was evaluated. Type of the filler and the extract/filler ratio but not the type of disintegrant determined fast disintegration of the tablets. It was demonstrated that the extract...