نتایج جستجو برای: super oxide radical

تعداد نتایج: 312267  

Journal: :applied food biotechnology 0
m.a sahari department of food science and technology, faculty of agriculture, tarbiat modares university, tehran, iran. s berenji ardestani department of food science and technology, faculty of agriculture, tarbiat modares university, tehran, iran.

bioactive food components (such as phenolic compounds, carotenoids, anthocyanins, tochopherols, ascorbic acid, flavonoids, minerals, enzymes and pectin) are active ingredients in food or dietary supplements, which proven to have an important role in health, and are safe for human consumption. these compounds exert their antioxidant effects by different mechanisms such as single electron transfe...

2009
P. Nilani N. Kasthuribai B. Duraisamy P. Dhamodaran S. Ravichandran K. Ilango B. Suresh

Asthmatic patients are more subjected to continuous oxidative stress. Roosting the antioxidant defenses of asthma patient could be beneficial as it may help thwart symptoms of the lung disease and asthma. Considering these facts different plant extracts and phytoconstituents with proven anti asthmatic property had been subjected to antioxidant study at various combinations using Diphenyl Vicryl...

Journal: :iranian journal of pharmaceutical research 0
nima hamzian medical physics research center, mashhad university of medical sciences, mashhad, iran maryam hashemi nanotechnology research center, school of pharmacy, mashhad university of medical sciences, mashhad, iran mahdi ghorbani medical physics research center, mashhad university of medical sciences, mashhad, iran mohammad hossein bahreyni toosi medical physics research center, mashhad university of medical sciences, mashhad, iran mohammad ramezani pharmaceutical research center, school of pharmacy, mashhad university of medical sciences, mashhad, iran

the aim of this study was to develop a novel multifunctional nanoparticle, which encapsulates spion and gemcitabine in plga±peg to form multifunctional drug delivery system. for this aim, super paramagnetic iron oxide nanoparticles (spions) were synthesized and encapsulated simultaneously with gemcitabine (gem) in plga±peg copolymers via w/o/w double emulsification method. optimum size and enca...

2009
Senlin Lu Rodger Duffin Craig Poland Paul Daly Fiona Murphy Ellen Drost William MacNee Vicki Stone Ken Donaldson

BACKGROUND There has been concern regarding risks from inhalation exposure to nanoparticles (NPs). The large number of particles requiring testing means that alternative approaches to animal testing are needed. OBJECTIVES We set out to determine whether short-term in vitro assays that assess intrinsic oxidative stress potential and membrane-damaging potency of a panel of metal oxide NPs can b...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2002
Toshiaki Kume Naoki Asai Hiroyuki Nishikawa Nariyasu Mano Taro Terauchi Ryota Taguchi Hisashi Shirakawa Fumitaka Osakada Hiroki Mori Naoki Asakawa Masahiro Yonaga Yukio Nishizawa Hachiro Sugimoto Shun Shimohama Hiroshi Katsuki Shuji Kaneko Akinori Akaike

Excess activation of glutamate receptors and production of free radicals including nitric oxide may result in severe and irreversible damage to the mammalian central nervous system (CNS), but endogenous defense systems that protect neurons from these insults are poorly understood. Here, we purified and isolated a neuroprotective substance, which has been named "serofendic acid," from a lipophil...

2008
Ramnik Singh Narinder Singh B.S. Saini Harwinder Singh Rao

OBJECTIVE To investigate the in vitro antioxidant activity of different fractions (R1, R2 and R3) obtained from pet ether extract of black pepper fruits (Piper nigrum Linn.) MATERIALS AND METHODS The fractions R1, R2 and R3 were eluted from pet ether and ethyl acetate in the ratio of 6:4, 5:5 and 4:6, respectively. 1,1-Diphenyl-2-picryl-hydrazyl (DPPH) radical, superoxide anion radical, nitri...

2011
S. Chaturvedi A. Joshi B. K. Dubey

Many herbal remedies have been employed in various medicine systems for the treatment and management of the different diseases. The Tamarinds indica commonly known as ‘imali’ has been recognized in different system of traditional medicines for the treatment of different diseases and aliments of human being. This review supports of all updated information on its pharmacognostical, pharmacologica...

Introduction: Diabetic foot ulcer is a serious complication of diabetes mellitus; it consists of lesions in the deep tissues associated with neurological disorders and peripheral vascular disease in the lower limbs. Delayed wound healing in diabetes leads to long-term hospitalization and even amputation of distal organs. Diabetes mellitus is associated with decreased nitric oxide bioavailabilit...

Journal: :The Journal of biological chemistry 1985
D Ross R J Mehlhorn P Moldeus M T Smith

Diethylstilbestrol is carcinogenic in rodents and in humans and its peroxidatic oxidation in utero has been associated with its carcinogenic activity. Horseradish peroxidase-catalyzed oxidation of [14C]diethylstilbestrol and [14C]diethylstilbestrol analogs induced binding of radiolabel to DNA only when the compound contained a free hydroxy group (Metzler, M., and Epe, B. (1984) Chem. Biol. Inte...

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